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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3911
Target Type SINGLE PROTEIN
Preferred Name Leukotriene B4 receptor 1
Synonyms BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LTB4-R 1 | LTB4-R1 | LTB4R | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > lipid-like ligand receptor (family a gpcr) > leukotriene receptor

Target Components

Component Description Relationship Accession
Leukotriene B4 receptor 1 SINGLE PROTEIN Q15722

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095160 Leukotriene B4 receptor PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000213903
Ensembl ENSG00000213903
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0000166 (nucleotide binding)
GO Biological Process GO:0006928 (cellular component movement)
GO:0006936 (muscle contraction)
GO:0006954 (inflammatory response)
GO:0006955 (immune response)
GO:0007200 (activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger)
Wikipedia Leukotriene_B4_receptor

Target Cross References - Protein

canSAR Q15722
Human Protein Atlas ENSG00000213903
Guide to Pharmacology 267 (BLT1)
PharmGKB PA30476
Reactome REACT_14797 (Signaling by GPCR.)
UniProt Q13305 Q15722 Q53XV5 Q92641 Q9BSU5

Target Cross References - Domain

InterPro IPR000276 (7TM_GPCR_Rhodpsn.)
IPR003981 (Leukotriene_B4_rcpt.)
IPR003983 (Leukotriene_B4_typ-1_rcpt.)
IPR017452 (GPCR_Rhodpsn_supfam.)
Pfam PF00001 (7tm_1)
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