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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3318
Target Type SINGLE PROTEIN
Preferred Name Tyrosinase
Synonyms Cresolase 2 | PPO2 | PPO2 | Phenolase 2 | Polyphenol oxidase 2 | Tyrosinase 2
Organism Agaricus bisporus
Species Group No
Protein Target Classification
  • enzyme > oxidoreductase

Target Components

Component Description Relationship Accession
Polyphenol oxidase 2 SINGLE PROTEIN O42713

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0004497 (monooxygenase activity)
GO:0004503 (monophenol monooxygenase activity)
GO:0016491 (oxidoreductase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0008152 (metabolic process)
GO:0042438 (melanin biosynthetic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

canSAR O42713
UniProt O42713 Q12543

Target Cross References - Domain

InterPro IPR002227 (Tyrosinase_Cu-bd.)
IPR008922 (Unchr_di-copper_centre.)
IPR016216 (Monophenol_mOase_fun.)
Pfam PF00264 (Tyrosinase)
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