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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3114
Target Type SINGLE PROTEIN
Preferred Name Sucrase-isomaltase
Synonyms Isomaltase | Si | Sucrase | Sucrase-isomaltase, intestinal
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Sucrase-isomaltase, intestinal SINGLE PROTEIN P23739

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005886 (plasma membrane)
GO:0005903 (brush border)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0016324 (apical plasma membrane)
GO:0045121 (membrane raft)
GO Molecular Function GO:0003824 (catalytic activity)
GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
GO:0004564 (beta-fructofuranosidase activity)
GO:0004574 (oligo-1,6-glucosidase activity)
GO:0004575 (sucrose alpha-glucosidase activity)
GO:0005515 (protein binding)
GO:0016787 (hydrolase activity)
GO:0016798 (hydrolase activity, acting on glycosyl bonds)
GO:0030246 (carbohydrate binding)
GO Biological Process GO:0005975 (carbohydrate metabolic process)
GO:0007568 (aging)
GO:0007584 (response to nutrient)
GO:0008152 (metabolic process)
GO:0009744 (response to sucrose)
GO:0009750 (response to fructose)
GO:0032868 (response to insulin)
GO:0033189 (response to vitamin A)
GO:0042594 (response to starvation)
GO:0051384 (response to glucocorticoid)

Target Cross References - Protein

canSAR P23739
UniProt P23739

Target Cross References - Domain

InterPro IPR000322 (Glyco_hydro_31.)
IPR000519 (P_trefoil_dom.)
IPR011013 (Gal_mutarotase_sf_dom.)
IPR013780 (Glyco_hydro_b.)
IPR017853 (Glycoside_hydrolase_SF.)
IPR017957 (P_trefoil_CS.)
IPR030458 (Glyco_hydro_31_AS.)
IPR030459 (Glyco_hydro_31_CS.)
IPR031727 (Gal_mutarotase_N.)
Pfam PF00088 (Trefoil)
PF01055 (Glyco_hydro_31)
PF16863 (NtCtMGAM_N)
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