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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2714
Target Type SINGLE PROTEIN
Preferred Name Pepsin A
Synonyms PGA | Pepsin A
Organism Sus scrofa
Species Group No
Protein Target Classification
  • enzyme > protease > aspartic protease > aspartic protease aa clan > aspartic protease a1a subfamily

Target Components

Component Description Relationship Accession
Pepsin A SINGLE PROTEIN P00791

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005576 (extracellular region)
GO Molecular Function GO:0004190 (aspartic-type endopeptidase activity)
GO:0008233 (peptidase activity)
GO:0016787 (hydrolase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0006914 (autophagy)
GO:0007586 (digestion)
GO:0030163 (protein catabolic process)

Target Cross References - Protein

canSAR P00791
Reactome R-SSC-5683826 (Surfactant metabolism.)
UniProt P00791 Q29080

Target Cross References - Domain

InterPro IPR001461 (Aspartic_peptidase_A1.)
IPR001969 (Aspartic_peptidase_AS.)
IPR012848 (Aspartic_peptidase_N.)
IPR021109 (Peptidase_aspartic_dom_sf.)
IPR033121 (PEPTIDASE_A1.)
IPR034162 (Pepsin_A.)
Pfam PF00026 (Asp)
PF07966 (A1_Propeptide)

Target Cross References - Structure

PDBe 1F34 1PSA 1YX9 2PSG 3PEP 3PSG 4PEP 5PEP
CREDO 1F34 1PSA 1YX9 2PSG 3PEP 3PSG 4PEP 5PEP
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