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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2595
Target Type SINGLE PROTEIN
Preferred Name Protein kinase C nu
Synonyms EPK2 | PRKCN | PRKD3 | Protein kinase C nu type | Protein kinase EPK2 | Serine/threonine-protein kinase D3 | nPKC-nu
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase pkd family

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase D3 SINGLE PROTEIN O94806

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2093867 Protein kinase C (PKC) PROTEIN FAMILY
CHEMBL2096620 Protein kinase C, PKC; classical/novel PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000115825
Ensembl ENSG00000115825
GO Cellular Component GO:0005654 (nucleoplasm)
GO:0005737 (cytoplasm)
GO:0016020 (membrane)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004697 (protein kinase C activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0007205 (protein kinase C-activating G-protein coupled receptor signaling pathway)
GO:0016310 (phosphorylation)
GO:0035556 (intracellular signal transduction)
Wikipedia PRKD3

Target Cross References - Protein

canSAR O94806
Human Protein Atlas ENSG00000115825
IntAct O94806
Guide to Pharmacology 2174
Open Targets ENSG00000115825
PharmGKB PA33772
Pharos O94806 (Tchem)
Reactome R-HSA-1660661 (Sphingolipid de novo biosynthesis.)
UniProt D6W587 O94806 Q53TR7 Q8NEL8

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR001849 (PH_domain.)
IPR002219 (PE/DAG-bd.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR011993 (PH_dom-like.)
IPR015727 (Protein_Kinase_C_mu-related.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR020454 (DAG/PE-bd.)
Pfam PF00069 (Pkinase)
PF00130 (C1_1)
PF00169 (PH)
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