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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2364027
Target Type SINGLE PROTEIN
Preferred Name Pyruvate:ferredoxin oxidoreductase
Synonyms Pyruvate:ferredoxin oxidoreductase
Organism Giardia intestinalis
Species Group No
Protein Target Classification
  • enzyme > oxidoreductase

Target Components

Component Description Relationship Accession
Pyruvate:ferredoxin oxidoreductase SINGLE PROTEIN Q24982

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL1401 NITAZOXANIDE Pyruvate:ferredoxin oxidoreductase inhibitor 4 DailyMed

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Molecular Function GO:0003824 (catalytic activity)
GO:0016491 (oxidoreductase activity)
GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors)
GO Biological Process GO:0008152 (metabolic process)
GO:0055114 (oxidation-reduction process)

Target Cross References - Protein

UniProt A8B8W2 Q24982

Target Cross References - Domain

InterPro IPR002869 (Pyrv_flavodox_OxRed_cen.)
IPR002880 (Pyrv_Fd/Flavodoxin_OxRdtase_N.)
IPR009014 (Transketo_C/PFOR_II.)
IPR017896 (4Fe4S_Fe-S-bd.)
IPR017900 (4Fe4S_Fe_S_CS.)
IPR019752 (Pyrv/ketoisovalerate_OxRed_cat.)
IPR029061 (THDP-binding.)
IPR033412 (PFOR_II.)
Pfam PF01558 (POR)
PF01855 (POR_N)
PF12838 (Fer4_7)
PF17147 (PFOR_II)
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