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ChEMBL

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Target Report Card

Target Name and Classification

Target ID CHEMBL2363135
Target Type PROTEIN NUCLEIC-ACID COMPLEX
Preferred Name Bacterial 70S ribosome
Synonyms
Organism Bacteria
Species Group Yes
Protein Target Classification
  • other cytosolic protein
  • unclassified protein

Target Components

Component Description Relationship Accession
30S ribosomal protein S2 PROTEIN SUBUNIT P0A7V0
50S ribosomal protein L4 PROTEIN SUBUNIT P60723
30S ribosomal protein S1 PROTEIN SUBUNIT P0AG67
30S ribosomal protein S10 PROTEIN SUBUNIT P0A7R5
30S ribosomal protein S11 PROTEIN SUBUNIT P0A7R9
30S ribosomal protein S12 PROTEIN SUBUNIT P0A7S3
30S ribosomal protein S13 PROTEIN SUBUNIT P0A7S9
30S ribosomal protein S14 PROTEIN SUBUNIT P0AG59
30S ribosomal protein S15 PROTEIN SUBUNIT P0ADZ4
30S ribosomal protein S16 PROTEIN SUBUNIT P0A7T3
30S ribosomal protein S17 PROTEIN SUBUNIT P0AG63
30S ribosomal protein S18 PROTEIN SUBUNIT P0A7T7
30S ribosomal protein S19 PROTEIN SUBUNIT P0A7U3
30S ribosomal protein S20 PROTEIN SUBUNIT P0A7U7
30S ribosomal protein S21 PROTEIN SUBUNIT P68679
30S ribosomal protein S3 PROTEIN SUBUNIT P0A7V3
30S ribosomal protein S4 PROTEIN SUBUNIT P0A7V8
30S ribosomal protein S5 PROTEIN SUBUNIT P0A7W1
30S ribosomal protein S6 PROTEIN SUBUNIT P02358
30S ribosomal protein S7 PROTEIN SUBUNIT P02359
30S ribosomal protein S8 PROTEIN SUBUNIT P0A7W7
30S ribosomal protein S9 PROTEIN SUBUNIT P0A7X3
50S ribosomal protein L10 PROTEIN SUBUNIT P0A7J3
50S ribosomal protein L11 PROTEIN SUBUNIT P0A7J7
50S ribosomal protein L13 PROTEIN SUBUNIT P0AA10
50S ribosomal protein L14 PROTEIN SUBUNIT P0ADY3
50S ribosomal protein L15 PROTEIN SUBUNIT P02413
50S ribosomal protein L16 PROTEIN SUBUNIT P0ADY7
50S ribosomal protein L17 PROTEIN SUBUNIT P0AG44
50S ribosomal protein L18 PROTEIN SUBUNIT P0C018
50S ribosomal protein L19 PROTEIN SUBUNIT P0A7K6
50S ribosomal protein L1 PROTEIN SUBUNIT P0A7L0
50S ribosomal protein L20 PROTEIN SUBUNIT P0A7L3
50S ribosomal protein L21 PROTEIN SUBUNIT P0AG48
50S ribosomal protein L22 PROTEIN SUBUNIT P61175
50S ribosomal protein L23 PROTEIN SUBUNIT P0ADZ0
50S ribosomal protein L24 PROTEIN SUBUNIT P60624
50S ribosomal protein L25 PROTEIN SUBUNIT P68919
50S ribosomal protein L27 PROTEIN SUBUNIT P0A7L8
50S ribosomal protein L28 PROTEIN SUBUNIT P0A7M2
50S ribosomal protein L29 PROTEIN SUBUNIT P0A7M6
50S ribosomal protein L2 PROTEIN SUBUNIT P60422
50S ribosomal protein L30 PROTEIN SUBUNIT P0AG51
50S ribosomal protein L31 type B PROTEIN SUBUNIT P0A7N1
50S ribosomal protein L31 PROTEIN SUBUNIT P0A7M9
50S ribosomal protein L32 PROTEIN SUBUNIT P0A7N4
50S ribosomal protein L33 PROTEIN SUBUNIT P0A7N9
50S ribosomal protein L34 PROTEIN SUBUNIT P0A7P5
50S ribosomal protein L35 PROTEIN SUBUNIT P0A7Q1
50S ribosomal protein L36 2 PROTEIN SUBUNIT Q2EEQ2
50S ribosomal protein L36 PROTEIN SUBUNIT P0A7Q6
50S ribosomal protein L3 PROTEIN SUBUNIT P60438
50S ribosomal protein L5 PROTEIN SUBUNIT P62399
50S ribosomal protein L6 PROTEIN SUBUNIT P0AG55
50S ribosomal protein L7/L12 PROTEIN SUBUNIT P0A7K2
5S ribosomal RNA RNA SUBUNIT
16S ribosomal RNA RNA SUBUNIT
23S ribosomal RNA RNA SUBUNIT

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL529 AZITHROMYCIN Bacterial 70S ribosome inhibitor 4 PubMed PubMed PubMed
CHEMBL532 ERYTHROMYCIN Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL126 LINEZOLID Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL130 CHLORAMPHENICOL Bacterial 70S ribosome inhibitor 4 PubMed PubMed
CHEMBL1136 TELITHROMYCIN Bacterial 70S ribosome inhibitor 4 DailyMed
CHEMBL376140 TIGECYCLINE Bacterial 70S ribosome inhibitor 4 DailyMed
CHEMBL1440 TETRACYCLINE Bacterial 70S ribosome inhibitor 4 FDA PubMed
CHEMBL1446 KANAMYCIN SULFATE Bacterial 70S ribosome inhibitor 4 PubMed
CHEMBL1506 CHLORAMPHENICOL PALMITATE Bacterial 70S ribosome inhibitor 4 PubMed PubMed
CHEMBL1517 OXYTETRACYCLINE Bacterial 70S ribosome inhibitor 4 KEGG
CHEMBL261772 MECLOCYCLINE SULFOSALICYLATE Bacterial 70S ribosome inhibitor 4 PubMed
CHEMBL454950 TETRACYCLINE HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 FDA PubMed
CHEMBL1741 CLARITHROMYCIN Bacterial 70S ribosome inhibitor 4 DailyMed PubMed PubMed
CHEMBL1164318 AMIKACIN SULFATE Bacterial 70S ribosome inhibitor 4 PubMed PubMed
CHEMBL1200474 DEMECLOCYCLINE HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 PubMed
CHEMBL1200506 ERYTHROMYCIN LACTOBIONATE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL1200510 ERYTHROMYCIN STEARATE Bacterial 70S ribosome inhibitor 4 FDA PubMed
CHEMBL1200588 CLINDAMYCIN HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL1200632 CLINDAMYCIN PALMITATE HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL1200649 QUINUPRISTIN Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL1200688 ERYTHROMYCIN ETHYLSUCCINATE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL1200729 CHLORAMPHENICOL SODIUM SUCCINATE Bacterial 70S ribosome inhibitor 4 PubMed PubMed
CHEMBL1200881 MINOCYCLINE HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 KEGG PubMed
CHEMBL1200937 DALFOPRISTIN Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL1201071 TETRACYCLINE PHOSPHATE COMPLEX Bacterial 70S ribosome inhibitor 4 FDA PubMed
CHEMBL1607480 OXYTETRACYCLINE HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 KEGG
CHEMBL2105669 TEDIZOLID PHOSPHATE Bacterial 70S ribosome inhibitor 4 FDA PubMed PubMed
CHEMBL2146063 CHLORTETRACYCLINE HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 PubMed
CHEMBL2146123 METHACYCLINE HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 PubMed PubMed PubMed PubMed
CHEMBL2206196 PAROMOMYCIN SULFATE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL2218877 ERYTHROMYCIN ESTOLATE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL3039471 DIRITHROMYCIN Bacterial 70S ribosome inhibitor 4 PubMed PubMed PubMed
CHEMBL3039594 GENTAMICIN SULFATE Bacterial 70S ribosome inhibitor 4 ISBN
CHEMBL3184512 CLINDAMYCIN PHOSPHATE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL3184791 STREPTOMYCIN SULFATE Bacterial 70S ribosome inhibitor 4 FDA PubMed
CHEMBL3188576 DIHYDROSTREPTOMYCIN SULFATE Bacterial 70S ribosome inhibitor 4 PubMed PubMed PubMed PubMed
CHEMBL3545060 ERYTHROMYCIN GLUCEPTATE Bacterial 70S ribosome inhibitor 4 DailyMed PubMed
CHEMBL3989568 OXYTETRACYCLINE CALCIUM Bacterial 70S ribosome inhibitor 4 KEGG
CHEMBL3989571 SPECTINOMYCIN HYDROCHLORIDE Bacterial 70S ribosome inhibitor 4 FDA PubMed
CHEMBL3989769 NEOMYCIN SULFATE Bacterial 70S ribosome inhibitor 4 PubMed PubMed PubMed PubMed
CHEMBL3989829 NETILMICIN SULFATE Bacterial 70S ribosome inhibitor 4 PubMed PubMed
More...

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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