ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL2363080
Target Type SINGLE PROTEIN
Preferred Name Voltage-activated calcium channel beta 2 subunit
Synonyms High voltage-activated calcium channel beta subunit CavB2
Organism Schistosoma mansoni
Species Group No
Protein Target Classification
  • auxiliary transport protein > calcium channel auxiliary subunit beta family

Target Components

Component Description Relationship Accession
High voltage-activated calcium channel beta subunit CavB2 SINGLE PROTEIN Q962H3

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL976 PRAZIQUANTEL Voltage-activated calcium channel beta 2 subunit blocker 4 PubMed PubMed

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

GO Cellular Component GO:0005891 (voltage-gated calcium channel complex)
GO Molecular Function GO:0005245 (voltage-gated calcium channel activity)
GO Biological Process GO:0070588 (calcium ion transmembrane transport)

Target Cross References - Protein

UniProt Q962H3

Target Cross References - Domain

InterPro IPR000584 (VDCC_L_bsu.)
IPR001452 (SH3_domain.)
IPR008145 (GK/Ca_channel_bsu.)
IPR027417 (P-loop_NTPase.)
Pfam PF00625 (Guanylate_kin)
spacer
spacer