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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2363052
Target Type PROTEIN COMPLEX
Preferred Name Glycine receptor (alpha-1/beta)
Synonyms GLRA1 | GLRB | Glycine receptor 48 kDa subunit | Glycine receptor 58 kDa subunit | Glycine receptor strychnine-binding subunit | Glycine receptor subunit alpha-1 | Glycine receptor subunit beta
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > ligand-gated ion channel > glycine receptor

Target Components

Component Description Relationship Accession
Glycine receptor subunit alpha-1 PROTEIN SUBUNIT P23415
Glycine receptor subunit beta PROTEIN SUBUNIT P48167

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL5845 Glycine receptor subunit alpha-1 SINGLE PROTEIN

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL931 HALOTHANE Glycine receptor (alpha-1/beta) positive modulator 4 PubMed PubMed PubMed
CHEMBL1256 ISOFLURANE Glycine receptor (alpha-1/beta) positive modulator 4 PubMed
CHEMBL1257 ENFLURANE Glycine receptor (alpha-1/beta) positive modulator 4 PubMed PubMed
CHEMBL1341 METHOXYFLURANE Glycine receptor (alpha-1/beta) agonist 4 PubMed PubMed
CHEMBL1200694 SEVOFLURANE Glycine receptor (alpha-1/beta) positive modulator 4 PubMed PubMed PubMed
CHEMBL1200733 DESFLURANE Glycine receptor (alpha-1/beta) positive modulator 4 PubMed

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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