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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL232
Preferred Name Alpha-1b adrenergic receptor
Synonyms ADRA1B | Alpha-1B adrenergic receptor | Alpha-1B adrenoceptor | Alpha-1B adrenoreceptor
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > adrenergic receptor

Target Components

Component Description Relationship Accession
Alpha-1B adrenergic receptor SINGLE PROTEIN P35368

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2096676 Adrenergic receptors; alpha-1 A & B SELECTIVITY GROUP
CHEMBL2094251 Adrenergic receptor alpha-1 PROTEIN FAMILY
CHEMBL2331074 Adrenergic receptor PROTEIN FAMILY
CHEMBL2095203 Adrenergic receptor alpha PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000170214
Ensembl ENSG00000170214
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0004937 (alpha1-adrenergic receptor activity)
GO Biological Process GO:0007188 (G-protein signaling, coupled to cAMP nucleotide second messenger)
GO:0007243 (intracellular protein kinase cascade)
GO:0007267 (cell-cell signaling)
GO:0008283 (cell proliferation)
Wikipedia Alpha-1B_adrenergic_receptor

Target Cross References - Protein

canSAR P35368
Human Protein Atlas ENSG00000170214
IntAct P35368
Guide to Pharmacology 23 (Alpha;1B-adrenoceptor)
PharmGKB PA33
Reactome REACT_14797 (Signaling by GPCR.)
UniProt B0LPE1 P35368

Target Cross References - Domain

InterPro IPR000276 (7TM_GPCR_Rhodpsn.)
IPR001115 (Adrene_rcpt_A1B.)
IPR002233 (Adrnrgc_rcpt.)
IPR017452 (GPCR_Rhodpsn_supfam.)
Pfam PF00001 (7tm_1)