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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2319
Target Type SINGLE PROTEIN
Preferred Name Kallikrein 1
Synonyms KLK1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > serine protease > serine protease pa clan > serine protease s1a subfamily

Target Components

Component Description Relationship Accession
Kallikrein-1 SINGLE PROTEIN P06870

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000167748
Ensembl ENSG00000167748
GO Cellular Component GO:0005634 (nucleus)
GO Molecular Function GO:0004252 (serine-type endopeptidase activity)
GO Biological Process GO:0006508 (proteolysis)
Wikipedia KLK1

Target Cross References - Protein

canSAR P06870
Human Protein Atlas ENSG00000167748
PharmGKB PA224
UniProt P06870 Q66US9 Q86U61 Q8TCV8 Q9BS53 Q9NQU4 Q9UD19 Q9UMJ1

Target Cross References - Domain

InterPro IPR001254 (Peptidase_S1_S6.)
IPR001314 (Peptidase_S1A.)
IPR009003 (Pept_cys/ser_Trypsin-like.)
IPR018114 (Peptidase_S1/S6_AS.)
Pfam PF00089 (Trypsin)

Target Cross References - Structure

PDBe 1SPJ
CREDO 1SPJ
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