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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2311225
Target Type PROTEIN COMPLEX
Preferred Name DNA gyrase
Synonyms DNA gyrase subunit A | DNA gyrase subunit B | gyrA | gyrB
Organism Streptococcus pneumoniae
Species Group No
Protein Target Classification
  • enzyme > isomerase

Target Components

Component Description Relationship Accession
DNA gyrase subunit B PROTEIN SUBUNIT P0A4L9
DNA gyrase subunit A PROTEIN SUBUNIT P72524

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL1075021 DNA gyrase subunit B SINGLE PROTEIN

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL31 GATIFLOXACIN DNA gyrase inhibitor 4 FDA
CHEMBL33 LEVOFLOXACIN DNA gyrase inhibitor 4 DailyMed
CHEMBL1200393 GREPAFLOXACIN HYDROCHLORIDE DNA gyrase inhibitor 4 PubMed PubMed PubMed
CHEMBL1200621 GEMIFLOXACIN MESYLATE DNA gyrase inhibitor 4 FDA

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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