ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL2095181
Target Type PROTEIN FAMILY
Preferred Name Opioid receptors; mu/kappa/delta
Synonyms D-OR-1 | DOR-1 | Delta-type opioid receptor | K-OR-1 | KOR-1 | Kappa-type opioid receptor | M-OR-1 | MOP | MOR-1 | MOR1 | Mu opiate receptor | Mu opioid receptor | Mu-type opioid receptor | OPRD | OPRD1 | OPRK | OPRK1 | OPRM1 | hMOP
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > short peptide receptor (family a gpcr) > opioid receptor

Target Components

Component Description Relationship Accession
Mu-type opioid receptor GROUP MEMBER P35372
Kappa-type opioid receptor GROUP MEMBER P41145
Delta-type opioid receptor GROUP MEMBER P41143

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095151 Opioid receptors; delta & kappa SELECTIVITY GROUP
CHEMBL233 Mu opioid receptor SINGLE PROTEIN
CHEMBL2095156 Opioid receptors; mu & kappa SELECTIVITY GROUP
CHEMBL236 Delta opioid receptor SINGLE PROTEIN
CHEMBL237 Kappa opioid receptor SINGLE PROTEIN
CHEMBL3883321 Mu opioid receptor/Alpha-2A adrenergic receptor PROTEIN COMPLEX
CHEMBL3885538 Cannabinoid receptor 1/Mu-type opioid receptor PROTEIN COMPLEX
CHEMBL3301384 CCR5/mu opioid receptor complex PROTEIN COMPLEX
CHEMBL2095149 Opioid receptors; mu & delta SELECTIVITY GROUP

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL19019 NALTREXONE Opioid receptors; mu/kappa/delta antagonist 4 DailyMed
CHEMBL284671 CODEINE SULFATE Opioid receptors; mu/kappa/delta agonist 4 PubMed PubMed
CHEMBL1718 NALOXONE HYDROCHLORIDE Opioid receptors; mu/kappa/delta antagonist 4 FDA PubMed
CHEMBL1200794 OXYMORPHONE HYDROCHLORIDE Opioid receptors; mu/kappa/delta agonist 4 DailyMed PubMed
CHEMBL1201099 CODEINE PHOSPHATE Opioid receptors; mu/kappa/delta agonist 4 PubMed PubMed
CHEMBL1201132 NALBUPHINE HYDROCHLORIDE Opioid receptors; mu/kappa/delta agonist 4 DailyMed
CHEMBL1201149 NALTREXONE HYDROCHLORIDE Opioid receptors; mu/kappa/delta antagonist 4 DailyMed
CHEMBL1201152 NALMEFENE HYDROCHLORIDE Opioid receptors; mu/kappa/delta antagonist 4 FDA
CHEMBL1201463 CODEINE POLISTIREX Opioid receptors; mu/kappa/delta agonist 4 PubMed PubMed
CHEMBL1201470 HYDROCODONE POLISTIREX Opioid receptors; mu/kappa/delta agonist 4 FDA PubMed
CHEMBL3833389 DEXTROMORAMIDE Opioid receptors; mu/kappa/delta agonist 4 PubMed PubMed
CHEMBL3989677 HYDROCODONE BITARTRATE Opioid receptors; mu/kappa/delta agonist 4 FDA PubMed
CHEMBL2364605 CEBRANOPADOL Opioid receptors; mu/kappa/delta agonist 3 PubMed PubMed
CHEMBL2103878 ODELEPRAN Opioid receptors; mu/kappa/delta antagonist 2 PubMed
More...

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

spacer
spacer