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Target Report Card

Target Name and Classification

Target ID CHEMBL2095180
Target Type PROTEIN FAMILY
Preferred Name Carbonic anhydrase
Synonyms CA-I | CA-II | CA-III | CA-IV | CA-IX | CA-VA | CA-VB | CA-VI | CA-VII | CA-XII | CA-XIII | CA-XIV | CA1 | CA12 | CA13 | CA14 | CA2 | CA3 | CA4 | CA5 | CA5A | CA5B | CA6 | CA7 | CA9 | CAB | CAC | CAIX | Carbonate dehydratase I | Carbonate dehydratase II | Carbonate dehydratase III | Carbonate dehydratase IV | Carbonate dehydratase IX | Carbonate dehydratase VA | Carbonate dehydratase VB | Carbonate dehydratase VI | Carbonate dehydratase VII | Carbonate dehydratase XII | Carbonate dehydratase XIII | Carbonate dehydratase XIV | Carbonic anhydrase 1 | Carbonic anhydrase 12 | Carbonic anhydrase 13 | Carbonic anhydrase 14 | Carbonic anhydrase 2 | Carbonic anhydrase 3 | Carbonic anhydrase 4 | Carbonic anhydrase 5A, mitochondrial | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 6 | Carbonic anhydrase 7 | Carbonic anhydrase 9 | Carbonic anhydrase B | Carbonic anhydrase C | Carbonic anhydrase I | Carbonic anhydrase II | Carbonic anhydrase III | Carbonic anhydrase IV | Carbonic anhydrase IX | Carbonic anhydrase VA | Carbonic anhydrase VB | Carbonic anhydrase VI | Carbonic anhydrase VII | Carbonic anhydrase XII | Carbonic anhydrase XIII | Carbonic anhydrase XIV | G250 | MN | Membrane antigen MN | P54/58N | RCC-associated antigen G250 | Renal cell carcinoma-associated antigen G250 | Salivary carbonic anhydrase | Secreted carbonic anhydrase | Tumor antigen HOM-RCC-3.1.3 | pMW1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > lyase

Target Components

Component Description Relationship Accession
Carbonic anhydrase 9 GROUP MEMBER Q16790
Carbonic anhydrase 6 GROUP MEMBER P23280
Carbonic anhydrase 12 GROUP MEMBER O43570
Carbonic anhydrase 1 GROUP MEMBER P00915
Carbonic anhydrase 13 GROUP MEMBER Q8N1Q1
Carbonic anhydrase 2 GROUP MEMBER P00918
Carbonic anhydrase 3 GROUP MEMBER P07451
Carbonic anhydrase 5B, mitochondrial GROUP MEMBER Q9Y2D0
Carbonic anhydrase 7 GROUP MEMBER P43166
Carbonic anhydrase 5A, mitochondrial GROUP MEMBER P35218
Carbonic anhydrase 14 GROUP MEMBER Q9ULX7
Carbonic anhydrase 4 GROUP MEMBER P22748

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3729 Carbonic anhydrase IV SINGLE PROTEIN
CHEMBL4789 Carbonic anhydrase VA SINGLE PROTEIN
CHEMBL3969 Carbonic anhydrase VB SINGLE PROTEIN
CHEMBL3025 Carbonic anhydrase VI SINGLE PROTEIN
CHEMBL2096906 Carbonic anhydrases; II & IX SELECTIVITY GROUP
CHEMBL205 Carbonic anhydrase II SINGLE PROTEIN
CHEMBL261 Carbonic anhydrase I SINGLE PROTEIN
CHEMBL3242 Carbonic anhydrase XII SINGLE PROTEIN
CHEMBL2111457 Carbonic anhydrase V PROTEIN FAMILY
CHEMBL2326 Carbonic anhydrase VII SINGLE PROTEIN
CHEMBL3510 Carbonic anhydrase XIV SINGLE PROTEIN
CHEMBL3594 Carbonic anhydrase IX SINGLE PROTEIN
CHEMBL2885 Carbonic anhydrase III SINGLE PROTEIN
CHEMBL3912 Carbonic anhydrase XIII SINGLE PROTEIN

Approved Drugs and Clinical Candidates

ChEMBL ID Name Mechanism of Action Max Phase References
CHEMBL18 ETHOXZOLAMIDE Carbonic anhydrase inhibitor 4 PubMed

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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