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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2094123
Target Type PROTEIN FAMILY
Preferred Name Serotonin (5-HT) receptor
Synonyms 5-HT-1A | 5-HT-1B | 5-HT-1C | 5-HT-1D | 5-HT-1F | 5-HT-2 | 5-HT-2A | 5-HT-2B | 5-HT-2C | 5-HT-2F | 5-HT-3 | 5-HT-4 | 5-HT-5A | 5-HT-5B | 5-HT-6 | 5-HT-7 | 5-HT-X | 5-HT1A | 5-HT1B | 5-HT1C | 5-HT1D | 5-HT1F | 5-HT2B | 5-HT2C | 5-HT3-A | 5-HT3-B | 5-HT3A | 5-HT3B | 5-HT3R | 5-HT4 | 5-HT5A | 5-HT5B | 5-HT6 | 5-HT7 | 5-HTR2C | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1B | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 1D | 5-hydroxytryptamine receptor 1F | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2B | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 3 | 5-hydroxytryptamine receptor 3A | 5-hydroxytryptamine receptor 3B | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 5A | 5-hydroxytryptamine receptor 5B | 5-hydroxytryptamine receptor 6 | 5-hydroxytryptamine receptor 7 | 5ht1a | 5ht1b | 5ht1c | 5ht1f | 5ht3 | 5ht5a | 5ht5b | GPRFO | Htr1a | Htr1b | Htr1c | Htr1d | Htr1f | Htr2 | Htr2a | Htr2b | Htr2c | Htr3 | Htr3a | Htr3b | Htr4 | Htr5a | Htr5b | Htr6 | Htr7 | MR22 | REC17 | ST-B17 | Serotonin receptor 1A | Serotonin receptor 1B | Serotonin receptor 1D | Serotonin receptor 1F | Serotonin receptor 2A | Serotonin receptor 2B | Serotonin receptor 2C | Serotonin receptor 3A | Serotonin receptor 3B | Serotonin receptor 4 | Serotonin receptor 5A | Serotonin receptor 5B | Serotonin receptor 6 | Serotonin receptor 7 | Serotonin-gated ion channel receptor | Srl | Stomach fundus serotonin receptor
Organism Rattus norvegicus
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > serotonin receptor
  • ion channel > ligand-gated ion channel > 5ht3 receptor

Target Components

Component Description Relationship Accession
5-hydroxytryptamine receptor 3B GROUP MEMBER Q9JJ16
5-hydroxytryptamine receptor 7 GROUP MEMBER P32305
5-hydroxytryptamine receptor 1F GROUP MEMBER P30940
5-hydroxytryptamine receptor 4 GROUP MEMBER Q62758
5-hydroxytryptamine receptor 2B GROUP MEMBER P30994
5-hydroxytryptamine receptor 1A GROUP MEMBER P19327
5-hydroxytryptamine receptor 2A GROUP MEMBER P14842
5-hydroxytryptamine receptor 5B GROUP MEMBER P35365
5-hydroxytryptamine receptor 1D GROUP MEMBER P28565
5-hydroxytryptamine receptor 2C GROUP MEMBER P08909
5-hydroxytryptamine receptor 5A GROUP MEMBER P35364
5-hydroxytryptamine receptor 6 GROUP MEMBER P31388
5-hydroxytryptamine receptor 3A GROUP MEMBER P35563
5-hydroxytryptamine receptor 1B GROUP MEMBER P28564

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL4655 Serotonin 5a (5-HT5a) receptor SINGLE PROTEIN
CHEMBL3372 Serotonin 6 (5-HT6) receptor SINGLE PROTEIN
CHEMBL2111398 Serotonin receptor 2a and 2b (5HT2A and 5HT2B) SELECTIVITY GROUP
CHEMBL2619 Serotonin 5b (5-HT5b) receptor SINGLE PROTEIN
CHEMBL2095159 Serotonin 1 (5-HT1) receptor PROTEIN FAMILY
CHEMBL3301381 Serotonin 1B/1D receptor PROTEIN FAMILY
CHEMBL2093870 Serotonin 2 (5-HT2) receptor PROTEIN FAMILY
CHEMBL2111406 Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) SELECTIVITY GROUP
CHEMBL322 Serotonin 2a (5-HT2a) receptor SINGLE PROTEIN
CHEMBL323 Serotonin 2b (5-HT2b) receptor SINGLE PROTEIN
CHEMBL273 Serotonin 1a (5-HT1a) receptor SINGLE PROTEIN
CHEMBL3459 Serotonin 1b (5-HT1b) receptor SINGLE PROTEIN
CHEMBL324 Serotonin 2c (5-HT2c) receptor SINGLE PROTEIN
CHEMBL5450 Serotonin 1d (5-HT1d) receptor SINGLE PROTEIN
CHEMBL2111383 Serotonin receptor 2a and 2c (5HT2A and 5HT2C) SELECTIVITY GROUP
CHEMBL3223 Serotonin 7 (5-HT7) receptor SINGLE PROTEIN
CHEMBL2097171 Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 SELECTIVITY GROUP
CHEMBL2411 Serotonin 3a (5-HT3a) receptor SINGLE PROTEIN
CHEMBL2097175 Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor SELECTIVITY GROUP
CHEMBL4646 Serotonin 1f (5-HT1f) receptor SINGLE PROTEIN
CHEMBL2094116 Serotonin 3 (5-HT3) receptor PROTEIN COMPLEX
CHEMBL4317 Serotonin 4 (5-HT4) receptor SINGLE PROTEIN

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

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