Target Report Card

Target Name and Classification

Target ID	CHEMBL2093869
Target Type	PROTEIN COMPLEX
Preferred Name	Integrin alpha-IIb/beta-3
Synonyms	CD_antigen=CD41 \| CD_antigen=CD61 \| GP2B \| GP3A \| GPIIIa \| GPIIb \| GPalpha IIb \| ITGA2B \| ITGAB \| ITGB3 \| Integrin alpha-IIb heavy chain \| Integrin alpha-IIb light chain, form 1 \| Integrin alpha-IIb light chain, form 2 \| Integrin alpha-IIb \| Integrin beta-3 \| Platelet membrane glycoprotein IIIa \| Platelet membrane glycoprotein IIb
Organism	Homo sapiens
Species Group	No
Protein Target Classification	membrane receptor

ChEMBL ID	Pref Name	Target Type
CHEMBL2111443	Integrin alpha-V/beta-3 and alpha-IIb/beta 3	SELECTIVITY GROUP
CHEMBL212	Integrin alpha-IIb	SINGLE PROTEIN
CHEMBL1907598	Integrin alpha-V/beta-3	PROTEIN COMPLEX
CHEMBL3883284	Integrin alpha-3/beta-3	PROTEIN COMPLEX
CHEMBL2111461	Integrin alpha-2/beta-3	PROTEIN COMPLEX
CHEMBL2111425	Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3)	PROTEIN COMPLEX GROUP

ChEMBL ID	Name	Mechanism of Action	Max Phase	References
CHEMBL1174	EPTIFIBATIDE	Integrin alpha-IIb/beta-3 inhibitor	4	DailyMed
CHEMBL1201584	ABCIXIMAB	Integrin alpha-IIb/beta-3 inhibitor	4	DailyMed
CHEMBL3189072	TIROFIBAN HYDROCHLORIDE	Integrin alpha-IIb/beta-3 inhibitor	4	DailyMed
CHEMBL1743076	TADOCIZUMAB	Integrin alpha-IIb/beta-3 antagonist	2	PubMed PubMed PubMed