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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1741195
Target Type SINGLE PROTEIN
Preferred Name Enteropeptidase
Synonyms ENTK | Enterokinase | Enteropeptidase catalytic light chain | Enteropeptidase non-catalytic heavy chain | Enteropeptidase | PRSS7 | Serine protease 7 | TMPRSS15 | Transmembrane protease serine 15
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > serine protease

Target Components

Component Description Relationship Accession
Enteropeptidase SINGLE PROTEIN P98073

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000154646
Ensembl ENSG00000154646
GO Cellular Component GO:0005903 (brush border)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004252 (serine-type endopeptidase activity)
GO:0005044 (scavenger receptor activity)
GO:0005515 (protein binding)
GO:0008233 (peptidase activity)
GO:0008236 (serine-type peptidase activity)
GO:0016787 (hydrolase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0006898 (receptor-mediated endocytosis)

Target Cross References - Protein

CGD Enterokinase deficiency
Human Protein Atlas ENSG00000154646
IntAct P98073
Open Targets ENSG00000154646
PharmGKB PA33839
UniProt P98073 Q2NKL7

Target Cross References - Domain

InterPro IPR000082 (SEA_dom.)
IPR000859 (CUB_dom.)
IPR000998 (MAM_dom.)
IPR001190 (SRCR.)
IPR001254 (Trypsin_dom.)
IPR001314 (Peptidase_S1A.)
IPR002172 (LDrepeatLR_classA_rpt.)
IPR009003 (Peptidase_S1_PA.)
IPR011163 (Pept_S1A_enterop.)
IPR013320 (ConA-like_dom_sf.)
IPR017448 (SRCR-like_dom.)
IPR018114 (TRYPSIN_HIS.)
IPR023415 (LDLR_class-A_CS.)
IPR033116 (TRYPSIN_SER.)
IPR035914 (Sperma_CUB_dom_sf.)
IPR036055 (LDL_receptor-like_sf.)
IPR036364 (SEA_dom_sf.)
IPR036772 (SRCR-like_dom_sf.)
Pfam PF00057 (Ldl_recept_a)
PF00089 (Trypsin)
PF00431 (CUB)
PF00629 (MAM)
PF01390 (SEA)
PF15494 (SRCR_2)

Target Cross References - Structure

PDBe 4DGJ
CREDO 4DGJ
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