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Target Report Card

Target Name and Classification

Target ID CHEMBL1628461
Preferred Name Oxoeicosanoid receptor 1
Synonyms 5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | Oxoeicosanoid receptor 1 | TG1019
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > lipid-like ligand receptor (family a gpcr) > leukotriene receptor

Target Components

Component Description Relationship Accession
Oxoeicosanoid receptor 1 SINGLE PROTEIN Q8TDS5

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000162881
Ensembl ENSG00000162881
GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0050646 (5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding)
GO:0050647 (5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding)
GO:0050648 (5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007193 (adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway)
Wikipedia Oxoeicosanoid_receptor_1

Target Cross References - Protein

Human Protein Atlas ENSG00000162881
IntAct Q8TDS5
Guide to Pharmacology 271
Open Targets ENSG00000162881
PharmGKB PA134983779
Pharos Q8TDS5 (Tchem)
Reactome R-HSA-391903 (Eicosanoid ligand-binding receptors.)
R-HSA-418594 (G alpha (i) signalling events.)
UniProt Q86WP7 Q8NGW4 Q8TDS5

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)