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Kinase SARfari

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Welcome to Kinase SARfari

Kinase SARfari is an integrated chemogenomics workbench focussed on Kinases. The system incorporates and links Kinase sequence, structure, compounds and screening data



Family Browsing Family Browsing

Access target information via Kinase SARfari classification

  • Browse Kinase groups, subgroups and families
  • Access target annotation summaries, report cards and alignments
  • Link through to screening and compound data

Search Kinase SARfari protein target data

  • Sequence search via BLAST
  • Comprehensive synonyms search
  • Access target annotation summaries, report cards and alignments
  • Link through to screening and compound data

Kinase binding site-based views and comparisons

  • Examine different views on inhibitor binding sites
  • Perform binding site comparisons and Neighbourhood Density analyses

Kinase SARfari 3D structural data

  • Search and retrieve structural summaries
  • View structure superpositions

Access Kinase SARfari screening data

  • Search with targets, compounds or both
  • Apply filters to bioactivity data
  • View and analyse cross-reactivity data

Search Kinase SARfari compound data

  • Perform substructure or similarity searches
  • Access compound summaries and report cards
  • Link through to screening and target data

Kinase SARfari User Guide contains

  • Application and project background details
  • Detailed workflow diagrams for the web interface
  • List of useful terms and concepts
  • FAQ section

Download Kinase SARfari data

  • Links to Kinase SARfari flatfile downloads

Kinase SARfari Contents

  • Kinase domains: 989
  • Kinase bioactivity datapoints: 532155
  • Kinase compounds: 54189
  • Version: 6.00
Protein Search Protein Search
Binding Site Binding Site
3D Structure 3D Structure
Bioactivity Searchh Bioactivity Searchh
Compound Search Compound Search
User Guide User Guide
User Guide User Guide
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