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Document Report Card

Doc ID CHEMBL3301361
Title Experimental in vitro DMPK and physicochemical data on a set of publicly disclosed compounds
Authors Mark Wenlock and Nicholas Tomkinson
Abstract Experimental data determined at AstraZeneca on a set of compounds in the following assays: pKa, lipophilicity (LogD7.4), aqueous solubility, plasma protein binding (human, rat, dog , mouse and guinea pig), intrinsic clearance (human liver microsomes, human and rat hepatocytes). The references provided for the assays exemplify the experimental procedures used in generating the data.
DOI http://dx.doi.org/10.6019/CHEMBL3301361

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