Structure-activity relationship data for chemical series of antagonists of the P2X7 receptor (Supplementary Bioactivity Data for publication CHEMBL1157114)
Senger S, Chau CH, Beswick PJ, Chambers LJ, Chessell IP, Davies DJ, Dean DK, Demont EH, Gleave R, Livermore DGH, Michel AD, Moses AP, Munoz-Muriedas J, Sime M, Steadman JGA, Theobald PJ, Thewlis RE, Trani G, Vimal M, Wall ID, Walter DS
Supplementary bioactivity data for the GlaxoSmithKline (GSK) publication Bioorg. Med. Chem. Lett. 2010, 20, 3161-3164 (ChEMBL Doc ID: CHEMBL1157114): pIC50 values for 725 compounds that have been tested in the ethidium bromide release assay (ChEMBL Assay ID: CHEMBL1103860) described in reference 24 of the aforementioned publication. All compounds have been tested at least four times and have been reported as being active in all test occasions. The standard deviation for all results is less than or equal to 0.5.