ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Document Report Card

Doc ID CHEMBL2094195
Title Structure-activity relationship data for a series of N-(phenylmehtyl)-2-(1H-pyrazol-4-yl)acetamide and N-(phenylmethyl)2-(4-isoxazolyl) acetamide antagonists of the P2X7 receptor (Supplementary Bioactivity Data for publication CHEMBL1157114)
Authors Senger S, Beswick PJ, Chambers LJ, Davies DJ, DK, Demont EH, Roomann S, Walters DS
Abstract Supplementary bioactivity data for the GlaxoSmithKline (GSK) publication Bioorg. Med. Chem. Lett. 2010, 20, 3161-3164 (ChEMBL Doc ID: CHEMBL1157114): pIC50 values for 54 compounds that have been tested in the ethidium bromide release assay (ChEMBL Assay ID: CHEMBL1103860) described in reference 24 of the aforementioned publication. All compounds have been tested at least four times and have been reported as being active in all test occasions.
DOI http://dx.doi.org/10.6019/CHEMBL2094195

Protein Target Summary

Assay Summary

Bioactivity Summary

Compound Summaries

spacer
spacer