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Compound Report CardCompound Name and Classification
Additional synonyms for CHEMBL846 found using NCI Chemical Identifier Resolver Compound Representations
Sources
Alternate Forms of Compound in ChEMBL
Molecule Features
Mechanism of Action
IndicationsClinical Data
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ChEMBL_ID | Target Name | Organism | Score |
CHEMBL1977 | Vitamin D receptor | Homo sapiens | 1.000 |
CHEMBL3150 | Vitamin D receptor | Rattus norvegicus | 1.000 |
CHEMBL4521 | Cytochrome P450 24A1 | Homo sapiens | 1.000 |
CHEMBL3746 | 11-beta-hydroxysteroid dehydrogenase 2 | Homo sapiens | 1.000 |
CHEMBL3056 | Androgen Receptor | Mus musculus | 1.000 |
CHEMBL3251 | Nuclear factor NF-kappa-B p105 subunit | Homo sapiens | 0.999 |
CHEMBL4931 | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | Homo sapiens | 0.999 |
CHEMBL3305 | Testis-specific androgen-binding protein | Homo sapiens | 0.991 |
CHEMBL3544 | Orphan nuclear receptor LRH-1 | Homo sapiens | 0.932 |
CHEMBL4666 | Steroidogenic factor 1 | Homo sapiens | 0.866 |
CHEMBL1293237 | Bloom syndrome protein | Homo sapiens | 0.864 |
CHEMBL2748 | Sucrase-isomaltase | Homo sapiens | 0.604 |
CHEMBL3041 | Mu opioid receptor | Bos taurus | 0.594 |
ChEMBL_ID | Target Name | Organism | Score |
CHEMBL3775 | Dual specificity phosphatase Cdc25A | Homo sapiens | 1.000 |
CHEMBL1977 | Vitamin D receptor | Homo sapiens | 1.000 |
CHEMBL3150 | Vitamin D receptor | Rattus norvegicus | 1.000 |
CHEMBL2027 | Niemann-Pick C1-like protein 1 | Homo sapiens | 1.000 |
CHEMBL4521 | Cytochrome P450 24A1 | Homo sapiens | 1.000 |
CHEMBL1697668 | Solute carrier organic anion transporter family member 1B1 | Homo sapiens | 1.000 |
CHEMBL1743121 | Solute carrier organic anion transporter family member 1B3 | Homo sapiens | 1.000 |
CHEMBL4804 | Dual specificity phosphatase Cdc25B | Homo sapiens | 1.000 |
CHEMBL4931 | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | Homo sapiens | 1.000 |
CHEMBL3746 | 11-beta-hydroxysteroid dehydrogenase 2 | Homo sapiens | 1.000 |
CHEMBL3262 | Lanosterol synthase | Rattus norvegicus | 1.000 |
CHEMBL3305 | Testis-specific androgen-binding protein | Homo sapiens | 1.000 |
CHEMBL4370 | UDP-glucuronosyltransferase 2B7 | Homo sapiens | 1.000 |
CHEMBL5356 | Cycloartenol synthase | Arabidopsis thaliana | 1.000 |
CHEMBL5355 | Lanosterol synthase | Saccharomyces cerevisiae S288c | 0.999 |
CHEMBL1828 | DNA polymerase alpha subunit | Homo sapiens | 0.999 |
CHEMBL5409 | G-protein coupled bile acid receptor 1 | Homo sapiens | 0.997 |
CHEMBL3056 | Androgen Receptor | Mus musculus | 0.997 |
CHEMBL3251 | Nuclear factor NF-kappa-B p105 subunit | Homo sapiens | 0.994 |
CHEMBL3180 | Carboxylesterase 2 | Homo sapiens | 0.977 |
Mol. Weight | Mol. Weight Monoisotopic | ALogP | #Rotatable Bonds | Polar Surface Area | Molecular Species |
416.6 | 416.329 | 5.18 | 6 | 60.69 | NEUTRAL |
HBA | HBD | #Ro5 Violations | HBA (Lipinski) | HBD (Lipinski) | #Ro5 Violations (Lipinski) |
3 | 3 | 1 | 3 | 3 | 1 |
ACD Acidic pKa | ACD Basic pKa | ACD LogP | ACD LogD pH7.4 | Aromatic Rings | Heavy Atoms | QED Weighted |
- | - | 5.63 | 5.63 | 0 | 30 | 0.56 |
ATC |
A - ALIMENTARY TRACT AND METABOLISM A11 - VITAMINS A11C - VITAMIN A AND D, INCL. COMBINATIONS OF THE TWO A11CC - Vitamin D and analogues A11CC04 - calcitriol D - DERMATOLOGICALS D05 - ANTIPSORIATICS D05A - ANTIPSORIATICS FOR TOPICAL USE D05AX - Other antipsoriatics for topical use D05AX03 - calcitriol |
ChemSpider | ChemSpider:GMRQFYUYWCNGIN-NKMMMXOESA-N |
DailyMed | calcitriol |
PubChem | SID: 144205541 SID: 26719902 SID: 50110818 |
Wikipedia | Calcitriol |
View the UniChem Connectivity matches for CHEMBL846