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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL532
CHEMBL532
Compound Name ERYTHROMYCIN
ChEMBL Synonyms WYAMYCIN S | ILOTYCIN | A/T/S | ERYTHROMYCIN GLUCOHEPTONATE | Ery-tab | C-SOLVE-2 | EMGEL | Erythra-Derm | R-p mycin | T-STAT | ERYTHROMYCIN STEARATE | ERYPAR | Erythro 200 | Eryc 125 | ERYTHROMYCIN | Erythro-Statin | ERYGEL | E-glades | E-base | ERYTHROMYCIN LACTOBIONATE | Akne-mycin | Robimycin | Pfizer-E | Ilotycin | ETHRIL 250 | BRISTAMYCIN | Sansac | Erythrocin | Erypar | Erycette | Benzamycin | ILOTYCIN GLUCEPTATE | Gallimycin | Erythromycin | Eryc sprinkles | ERYC | PFIZER-E | ERYTHROMYCIN GLUCEPTATE | ETHRIL 500 | ERYTHROCIN STEARATE | Wyamycin | Staticin | PCE | ERYMAX | ERYDERM | E-solve 2 | E-Mycin | Bristamycin | ERYTHROCIN
Max Phase 4 (Approved)
Trade Names A/T/S | Ery-tab | WYAMYCIN S | ERYTHRO-STATIN | Eryc 125 | Erythro 200 | ERYPAR | ERYTHROMYCIN STEARATE | E-base | E-glades | ERYGEL | ERYTHROMYCIN | Akne-mycin | Ilotycin | Robimycin | BRISTAMYCIN | ETHRIL 250 | ERYTHROMYCIN LACTOBIONATE | E-mycin | Erycette | Erythrocin | Sansac | ILOTYCIN GLUCEPTATE | ERYC | Eryc sprinkles | Erythromycin | Gallimycin | PFIZER-E | E-solve 2 | ERYDERM | ERYMAX | Staticin | Wyamycin | ERYTHROCIN STEARATE | ETHRIL 500 | C-SOLVE-2 | EMGEL | Erythra-Derm | R-p mycin | T-STAT | ERYTHROCIN | ILOTYCIN
Molecular Formula C37H67NO13

Additional synonyms for CHEMBL532 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C ...
Download SMILES
Standard InChI InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2) ...
Download InChI
Standard InChI Key ULGZDMOVFRHVEP-RWJQBGPGSA-N

Sources

  • British National Formulary
  • Curated Drug Metabolism Pathways
  • DrugMatrix
  • HeCaToS Compounds
  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • TP-search Transporter Database
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL532

Molecule Features

CHEMBL532 compound icon
Drug Type:Natural Product-derived Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:Y Topical:Y Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Bacterial 70S ribosome inhibitor Bacterial 70S ribosome DailyMed DailyMed DailyMed FDA PubMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
GASTROINTESTINAL HEMORRHAGED006471HP:0002239GASTROINTESTINAL HEMORRHAGE3ClinicalTrials
HEPATITIS CD006526EFO:0003047HEPATITIS C INFECTION1ClinicalTrials
COLORECTAL NEOPLASMSD015179EFO:0000365COLORECTAL ADENOCARCINOMA2ClinicalTrials
DIABETES MELLITUS, TYPE 1D003922EFO:0001359TYPE I DIABETES MELLITUS1ClinicalTrials
GASTROPARESISD018589EFO:1000948GASTROPARESIS2ClinicalTrials
STOMACH NEOPLASMSD013274EFO:0003897STOMACH NEOPLASM2ClinicalTrials

Clinical Data

ClinicalTrials.gov ERYTHROMYCIN
The Cochrane Collaboration ERYTHROMYCIN

Metabolites for CHEMBL532

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Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
733.9 733.4612 1.79 7 193.9 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
14 5 2 14 5 1


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
13.09 8.16 1.91 1.16 0 51 0.24

Structural Alerts

There are 3 structural alerts for CHEMBL532. To view alerts please click here.

Compound Cross References

ATC J - ANTIINFECTIVES FOR SYSTEMIC USE
J01 - ANTIBACTERIALS FOR SYSTEMIC USE
J01F - MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
J01FA - Macrolides
J01FA01 - erythromycin

D - DERMATOLOGICALS
D10 - ANTI-ACNE PREPARATIONS
D10A - ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF - Antiinfectives for treatment of acne
D10AF02 - erythromycin

D - DERMATOLOGICALS
D10 - ANTI-ACNE PREPARATIONS
D10A - ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF - Antiinfectives for treatment of acne
D10AF52 - erythromycin, combinations

S - SENSORY ORGANS
S01 - OPHTHALMOLOGICALS
S01A - ANTIINFECTIVES
S01AA - Antibiotics
S01AA17 - erythromycin

ChemSpider ChemSpider:ULGZDMOVFRHVEP-RWJQBGPGSA-N
DailyMed erythromycin erythromycin lactobionate erythromycin stearate
PubChem SID: 144204864 SID: 144205422 SID: 144210833 SID: 49675035
Wikipedia Erythromycin

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL532



ACToR 114-07-8 82343-12-2
BindingDB 50344942
Brenda 5148 106012 41741 106013
ChEBI 42355
DrugBank DB00199
DrugCentral 1048
eMolecules 6842882 2725491 29917758 2725679
EPA CompTox Dashboard DTXSID4022991
FDA SRS 63937KV33D
Guide to Pharmacology 1456
Human Metabolome Database HMDB0014344
IBM Patent System 6455E4F2683FA18CC12AA37A715CB221
KEGG Ligand C01912
LINCS LSM-3416
LipidMaps LMPK04000006
Mcule MCULE-4566208867
Metabolights MTBLC42355
Nikkaji J2.892D
PDBe ERY
PharmGKB PA449493
PubChem 12560
PubChem: Drugs of the Future 12012581
PubChem: Thomson Pharma 14864494 14840178
SureChEMBL SCHEMBL2601
ZINC ZINC000085534336

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/ULGZDMOVFRHVEP-RWJQBGPGSA-N spacer
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