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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL507870
CHEMBL507870
Compound Name TELAVANCIN
ChEMBL Synonyms VIBATIV | TD-6424 | TELAVANCIN | TELAVANCIN HYDROCHLORIDE
Max Phase 4 (Approved)
Trade Names VIBATIV
Molecular Formula C80H106Cl2N11O27P

Additional synonyms for CHEMBL507870 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CCCCCCCCCCNCCN[C@@]1(C)C[C@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H ...
Download SMILES
Standard InChI InChI=1S/C80H106Cl2N11O27P/c1-7-8-9-10-11-12-13-14-21-85-22- ...
Download InChI
Standard InChI Key ONUMZHGUFYIKPM-MXNFEBESSA-N

Sources

  • Orange Book
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL507870

Molecule Features

CHEMBL507870 compound icon
Drug Type:Natural Product-derived Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Cell outer membrane inhibitor Cell outer membrane FDA

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
InfectionD007239EFO:0000544infection2ClinicalTrials
Staphylococcal Skin InfectionsD013207EFO:1001849staphylococcal skin infections3ClinicalTrials
BacteremiaD016470EFO:0003033bacteriemia3ClinicalTrials
Pneumonia, BacterialD018410EFO:1001272bacterial pneumonia4DailyMed
DailyMed
ClinicalTrials
Renal Insufficiency, ChronicD051436EFO:0003884chronic kidney disease1ClinicalTrials

Clinical Data

ClinicalTrials.gov TELAVANCIN
The Cochrane Collaboration TELAVANCIN

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
1755.7 1753.6374 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL507870

Compound Cross References

ATC J - ANTIINFECTIVES FOR SYSTEMIC USE
J01 - ANTIBACTERIALS FOR SYSTEMIC USE
J01X - OTHER ANTIBACTERIALS
J01XA - Glycopeptide antibacterials
J01XA03 - telavancin

ChemSpider ChemSpider:ONUMZHGUFYIKPM-MXNFEBESSA-N
DailyMed telavancin hydrochloride

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL507870



ACToR 372151-71-8
ChEBI 71229
DrugBank DB06402
DrugCentral 4116
FDA SRS XK134822Z0
IBM Patent System B5302A27E6FFFE3A457AABFE0500F15D
Nikkaji J2.013.711H
PubChem 3081362
PubChem: Thomson Pharma 14842352 14817650
SureChEMBL SCHEMBL8287015

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/ONUMZHGUFYIKPM-MXNFEBESSA-N spacer
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