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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL3039583
CHEMBL3039583
Compound Name PASIREOTIDE
ChEMBL Synonyms PASIREOTIDE PAMOATE | PASIREOTIDE DIASPARTATE | SOM230 | PASIREOTIDE
Max Phase 4 (Approved)
Trade Names
Molecular Formula C58H66N10O9

Additional synonyms for CHEMBL3039583 found using NCI Chemical Identifier Resolver

Sources

  • British National Formulary
  • Orange Book
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL3039583 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Somatostatin receptor 1 agonist Somatostatin receptor 1 DailyMed DailyMed PubMed PubMed
Somatostatin receptor 2 agonist Somatostatin receptor 2 DailyMed DailyMed PubMed PubMed
Somatostatin receptor 3 agonist Somatostatin receptor 3 DailyMed DailyMed PubMed PubMed
Somatostatin receptor 5 agonist Somatostatin receptor 5 DailyMed DailyMed PubMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
MENINGIOMAD008579Orphanet:2495MENINGIOMA2ClinicalTrials
ACROMEGALYD000172EFO:1001485ACROMEGALY4DailyMed
ClinicalTrials
CARCINOID TUMORD002276EFO:0004243CARCINOID TUMOR3ClinicalTrials
BREAST NEOPLASMSD001943EFO:0000305BREAST CARCINOMA2ClinicalTrials
LUNG NEOPLASMSD008175EFO:0001071LUNG CARCINOMA2ClinicalTrials
PROSTATIC NEOPLASMSD011471EFO:0001663PROSTATE CARCINOMA2ClinicalTrials
CARCINOMA, HEPATOCELLULARD006528EFO:0000182HEPATOCELLULAR CARCINOMA2ClinicalTrials
PANCREATIC NEOPLASMSD010190EFO:0002618PANCREATIC CARCINOMA3ClinicalTrials
THYROID NEOPLASMSD013964EFO:0002892THYROID CARCINOMA2ClinicalTrials
ADENOMAD000236EFO:0000232ADENOMA2ClinicalTrials
CARCINOMA, MERKEL CELLD015266EFO:1001471MERKEL CELL SKIN CANCER1ClinicalTrials
HYPERGLYCEMIAD006943HP:0003074HYPERGLYCEMIA2ClinicalTrials
HYPERPLASIAD006965EFO:0000536HYPERPLASIA1ClinicalTrials
NEOPLASMSD009369EFO:0000311CANCER2ClinicalTrials
NEOPLASMSD009369EFO:0000616NEOPLASM2ClinicalTrials
POSTOPERATIVE COMPLICATIONSD011183EFO:0005323POST-OPERATIVE SIGN OR SYMPTOM2ClinicalTrials

Clinical Data

ClinicalTrials.gov PASIREOTIDE
The Cochrane Collaboration PASIREOTIDE

HELM Notation

CHEMBL3039583 HELM Notation
PEPTIDE1{[Phg].[dW].K.[Tyr(Bzl)].F.[X1765]}$PEPTIDE1,PEPTIDE1,6:R2-1:R1$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Cross References

ATC H - SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H01 - PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
H01C - HYPOTHALAMIC HORMONES
H01CB - Somatostatin and analogues
H01CB05 - pasireotide

ChemSpider ChemSpider:VMZMNAABQBOLAK-IXZCVAHUSA-N
DailyMed pasireotide diaspartate pasireotide pamoate

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL3039583



PubChem 73348210

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/VMZMNAABQBOLAK-IXZCVAHUSA-N spacer
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