ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Compound Report Card

Compound Name and Classification

Compound ID CHEMBL266481
CHEMBL266481
Compound Name GLUCAGON
ChEMBL Synonyms Glucagon Emergency Kit | GLUCAGON RECOMBINANT | GlucaGen Hypokit | GLUCAGON
Max Phase 4 (Approved)
Trade Names Glucagon Emergency Kit | GLUCAGON | GlucaGen Hypokit
Molecular Formula C153H225N43O49S

Additional synonyms for CHEMBL266481 found using NCI Chemical Identifier Resolver

Sources

  • British National Formulary
  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL266481 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Glucagon receptor agonist Glucagon receptor PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Diabetes Mellitus, Type 1D003922EFO:0001359type I diabetes mellitus3ClinicalTrials
ObesityD009765EFO:0001073obesity1ClinicalTrials
Diabetes Mellitus, Type 2D003924EFO:0001360type II diabetes mellitus3ClinicalTrials
Congenital HyperinsulinismD044903Orphanet:657Congenital isolated hyperinsulinism2ClinicalTrials
HypoglycemiaD007003HP:0001943Hypoglycemia3ClinicalTrials
Diabetes MellitusD003920EFO:0000400diabetes mellitus3ClinicalTrials

Clinical Data

ClinicalTrials.gov GLUCAGON
The Cochrane Collaboration GLUCAGON

HELM Notation

CHEMBL266481 HELM Notation
PEPTIDE1{H.S.Q.G.T.F.T.S.D.Y.S.K.Y.L.D.S.R.R.A.Q.D.F.V.Q.W.L.M.N.T}$$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ATC H - SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H04 - PANCREATIC HORMONES
H04A - GLYCOGENOLYTIC HORMONES
H04AA - Glycogenolytic hormones
H04AA01 - glucagon

ChemSpider ChemSpider:MASNOZXLGMXCHN-ZLPAWPGGSA-N
DailyMed glucagon recombinant
PubChem SID: 50112436
Wikipedia Glucagon

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL266481



BindingDB 50098571
Brenda 96251
ChEBI 5391
DrugCentral 2994
Guide to Pharmacology 1136
MolPort MolPort-003-938-762 MolPort-009-194-178
Nikkaji J9.063H
PubChem 77077981 16133817 16132283 44278361 102331734
PubChem: Thomson Pharma 15486417
SureChEMBL SCHEMBL15268863

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/MASNOZXLGMXCHN-ZLPAWPGGSA-N spacer
spacer