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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2111187
CHEMBL2111187
Compound Name RADIUM DICHLORIDE
ChEMBL Synonyms XOFIGO | BAY 88-8223 | RADIUM RA 223 DICHLORIDE | RADIUM (223RA) DICHLORIDE | RADIUM RA-223 DICHLORIDE
Max Phase 4 (Approved)
Trade Names BAY 88-8223 | XOFIGO
Molecular Formula Cl2Ra

Additional synonyms for CHEMBL2111187 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES [Cl-].[Cl-].[Ra+2]
Standard InChI InChI=1S/2ClH.Ra/h2*1H;/q;;+2/p-2
Standard InChI Key RWRDJVNMSZYMDV-UHFFFAOYSA-L

Sources

  • Orange Book
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL2111187

Molecule Features

CHEMBL2111187 compound icon
Drug Type:Inorganic Rule of Five:N First In Class:N Chirality:Unknown Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Radiotherapy agent Not Available DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
NeoplasmsD009369EFO:0000616neoplasm1ClinicalTrials
Prostatic NeoplasmsD011471EFO:0001663prostate carcinoma3ClinicalTrials
Prostatic NeoplasmsD011471EFO:0000673prostate adenocarcinoma3ClinicalTrials
Multiple MyelomaD009101EFO:0001378multiple myeloma1ClinicalTrials
Prostatic NeoplasmsD011471EFO:0000196metastatic prostate cancer3ClinicalTrials
Breast NeoplasmsD001943EFO:0003869breast neoplasm2ClinicalTrials

Clinical Data

ClinicalTrials.gov RADIUM DICHLORIDE
The Cochrane Collaboration RADIUM DICHLORIDE

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
296.9 292.9562 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL2111187

Compound Cross References

ATC V - VARIOUS
V10 - THERAPEUTIC RADIOPHARMACEUTICALS
V10X - OTHER THERAPEUTIC RADIOPHARMACEUTICALS
V10XX - Various therapeutic radiopharmaceuticals
V10XX03 - radium (223Ra) dichloride

ChemSpider ChemSpider:RWRDJVNMSZYMDV-UHFFFAOYSA-L
DailyMed radium ra-223 dichloride

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL2111187



FDA SRS KKO873WR2Z
Nikkaji J43.974F
SureChEMBL SCHEMBL162394

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/RWRDJVNMSZYMDV-UHFFFAOYSA-L spacer
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