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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2108429
CHEMBL2108429
Compound Name MEPOLIZUMAB
ChEMBL Synonyms MEPOLIZUMAB | NUCALA | SB-240563 | BOSATRIA
Max Phase 4 (Approved)
Trade Names NUCALA | BOSATRIA

Sources

  • British National Formulary
  • Clinical Candidates
  • Manually Added Drugs
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL2108429 compound icon
Drug Type:Antibody Rule of Five:N First In Class:Y Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Interleukin-5 inhibitor Interleukin-5 DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Churg-Strauss SyndromeD015267EFO:0007208Churg-Strauss syndrome3ClinicalTrials
Dermatitis, AtopicD003876EFO:0000274atopic eczema2ClinicalTrials
Eosinophilic EsophagitisD057765EFO:0004232eosinophilic esophagitis2ClinicalTrials
Hypereosinophilic SyndromeD017681EFO:1001467Hypereosinophilic syndrome3ClinicalTrials
AsthmaD001249EFO:0000270asthma4ClinicalTrials
DailyMed
Pulmonary Disease, Chronic ObstructiveD029424EFO:0000341chronic obstructive pulmonary disease3ClinicalTrials
Adenomatous Polyposis ColiD011125EFO:0000662polyp3ClinicalTrials
Lung Diseases, ObstructiveD008173HP:0006536obstructive lung disease4ATC

Clinical Data

ClinicalTrials.gov MEPOLIZUMAB
The Cochrane Collaboration MEPOLIZUMAB

Compound Cross References

ATC R - RESPIRATORY SYSTEM
R03 - DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03D - OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03DX - Other systemic drugs for obstructive airway diseases
R03DX09 - mepolizumab

ChemSpider ChemSpider Identifier not yet assigned
DailyMed mepolizumab
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