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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2108074
CHEMBL2108074
Compound Name PANCRELIPASE
ChEMBL Synonyms VIOKASE | ENTOLASE | COTAZYM | PANCRELIPASE (AMYLASE;LIPASE;PROTEASE) | PANCREASE | ACCELERASE | PANCRELIPASE | CREON | ILOZYME | LIPANCREATIN | KU-ZYME HP | COTAZYM-S | ZYMASE
Max Phase 4 (Approved)
Trade Names COTAZYM | ENTOLASE | VIOKASE | ACCELERASE | PANCREASE | ILOZYME | CREON | ZYMASE | COTAZYM-S | KU-ZYME HP

Sources

  • Orange Book
  • USP Dictionary of USAN and International Drug Names

Molecule Features

CHEMBL2108074 compound icon
Drug Type:Enzyme Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Fatty acids hydrolytic enzyme Fatty acids DailyMed
Polypeptides hydrolytic enzyme Polypeptides DailyMed
Starch hydrolytic enzyme Starch DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Pancreatic NeoplasmsD010190EFO:0002618pancreatic carcinoma1ClinicalTrials
PancreatitisD010195EFO:0000278pancreatitis2ClinicalTrials
Cystic FibrosisD003550Orphanet:586Cystic fibrosis3ClinicalTrials
Pancreatitis, ChronicD050500EFO:0000342chronic pancreatitis3ClinicalTrials
Renal Insufficiency, ChronicD051436EFO:0003884chronic kidney disease3ClinicalTrials
HypoglycemiaD007003HP:0001943Hypoglycemia1ClinicalTrials

Clinical Data

ClinicalTrials.gov PANCRELIPASE
The Cochrane Collaboration PANCRELIPASE

Compound Cross References

ATC A - ALIMENTARY TRACT AND METABOLISM
A09 - DIGESTIVES, INCL. ENZYMES
A09A - DIGESTIVES, INCL. ENZYMES
A09AA - Enzyme preparations
A09AA02 - multienzymes (lipase, protease etc.)

ChemSpider ChemSpider Identifier not yet assigned
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