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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2107857
CHEMBL2107857
Compound Name METRELEPTIN
ChEMBL Synonyms METRELEPTIN | R-METHULEPTIN
Max Phase 4 (Approved)
Trade Names

Sources

  • Manually Added Drugs
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL2107857 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:Y Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Leptin receptor agonist Leptin receptor FDA

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
LIPODYSTROPHYD008060EFO:1000727LIPODYSTROPHY4DailyMed
ClinicalTrials
OBESITYD009765EFO:0001073OBESITY3ClinicalTrials
DIABETES MELLITUS, TYPE 1D003922EFO:0001359TYPE I DIABETES MELLITUS1ClinicalTrials
NON-ALCOHOLIC FATTY LIVER DISEASED065626EFO:0003095NON-ALCOHOLIC FATTY LIVER DISEASE2ClinicalTrials

Clinical Data

ClinicalTrials.gov METRELEPTIN
The Cochrane Collaboration METRELEPTIN

Compound Cross References

ATC A - ALIMENTARY TRACT AND METABOLISM
A16 - OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16A - OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16AA - Amino acids and derivatives
A16AA07 - metreleptin

ChemSpider ChemSpider Identifier not yet assigned
DailyMed metreleptin
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