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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2104391
CHEMBL2104391
Compound Name INSULIN DETEMIR
ChEMBL Synonyms LEVEMIR INNOLET | LEVEMIR FLEXTOUCH | NN-304 | LEVEMIR FLEXPEN | INS LEVEMIR | INSULIN DETEMIR | LEVEMIR PENFILL | LEVEMIR | INSULIN DETEMIR RECOMBINANT
Max Phase 4 (Approved)
Trade Names INS LEVEMIR | LEVEMIR FLEXPEN | LEVEMIR FLEXTOUCH | LEVEMIR INNOLET | LEVEMIR | LEVEMIR PENFILL
Molecular Formula C267H402N64O76S6

Additional synonyms for CHEMBL2104391 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N ...
Download SMILES
Standard InChI InChI=1S/C267H402N64O76S6/c1-29-32-33-34-35-36-37-38-39-40-5 ...
Download InChI
Standard InChI Key UGOZVNFCFYTPAZ-IOXYNQHNSA-N

Sources

  • British National Formulary
  • Orange Book
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Alternate Forms of Compound in ChEMBL


CHEMBL2104391

Molecule Features

CHEMBL2104391 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Insulin receptor agonist Insulin receptor DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Diabetes Mellitus, Type 2D003924EFO:0001360type II diabetes mellitus4ClinicalTrials
DailyMed
Diabetes MellitusD003920EFO:0000400diabetes mellitus4ATC
ClinicalTrials
Diabetes Mellitus, Type 1D003922EFO:0001359type I diabetes mellitus4ClinicalTrials
DailyMed
Cystic FibrosisD003550Orphanet:586Cystic fibrosis2ClinicalTrials

Clinical Data

ClinicalTrials.gov INSULIN DETEMIR
The Cochrane Collaboration INSULIN DETEMIR

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
5916.9 5912.7883 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL2104391

Compound Cross References

ATC A - ALIMENTARY TRACT AND METABOLISM
A10 - DRUGS USED IN DIABETES
A10A - INSULINS AND ANALOGUES
A10AE - Insulins and analogues for injection, long-acting
A10AE05 - insulin detemir

ChemSpider ChemSpider:UGOZVNFCFYTPAZ-IOXYNQHNSA-N
DailyMed insulin detemir recombinant

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL2104391




UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/UGOZVNFCFYTPAZ-IOXYNQHNSA-N spacer
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