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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2103784
CHEMBL2103784
Compound Name COSYNTROPIN
ChEMBL Synonyms SYNACTHEN DEPOT | VICOTROPE | TETRACOSACTRIN | TETRACOSACTIDE ACETATE | CORTROSYN | TETRACOSACTIDE | SYNACTHEN | COSYNTROPIN | CORTICOTROPIN TETRACOSAPEPTIDE
Max Phase 4 (Approved)
Trade Names SYNACTHEN DEPOT | COSYNTROPIN | SYNACTHEN | CORTROSYN
Molecular Formula C136H210N40O31S

Additional synonyms for CHEMBL2103784 found using NCI Chemical Identifier Resolver

Sources

  • British National Formulary
  • Orange Book
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL2103784 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Melanocortin receptor 2 agonist Melanocortin receptor 2 DailyMed IUPHAR

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Glomerulonephritis, MembranousD015433EFO:0004254membranous glomerulonephritis2ClinicalTrials
Muscular Dystrophy, DuchenneD020388Orphanet:98896Duchenne muscular dystrophy2ClinicalTrials
HeadacheD006261HP:0002315Headache2ClinicalTrials

Clinical Data

ClinicalTrials.gov COSYNTROPIN
The Cochrane Collaboration COSYNTROPIN

HELM Notation

CHEMBL2103784 HELM Notation
PEPTIDE1{S.Y.S.M.E.H.F.R.W.G.K.P.V.G.K.K.R.R.P.V.K.V.Y.P}$$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ATC H - SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H01 - PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
H01A - ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
H01AA - ACTH
H01AA02 - tetracosactide

ChemSpider ChemSpider:ZOEFCCMDUURGSE-SQKVDDBVSA-N
DailyMed cosyntropin

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL2103784



BindingDB 50017180
ChEBI 3901
DrugBank DB01284
DrugCentral 4516
eMolecules 35862440
IBM Patent System 09573B7ABBF5B0FFA886B3D8C7BAE538
MolPort MolPort-009-194-172
PubChem 129627786 16133751 60210072 16133802
PubChem: Thomson Pharma 14793473
SureChEMBL SCHEMBL33366

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/ZOEFCCMDUURGSE-SQKVDDBVSA-N spacer
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