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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL2103749
CHEMBL2103749
Compound Name BIVALIRUDIN
ChEMBL Synonyms Angiox | BIVALIRUDIN TRIFLUOROACETATE | BG8967 | Angiomax | BIVALIRUDIN | ANGIOMAX
Max Phase 4 (Approved)
Trade Names Angiox | ANGIOMAX | BIVALIRUDIN | Angiomax
Molecular Formula C98H138N24O33

Additional synonyms for CHEMBL2103749 found using NCI Chemical Identifier Resolver

Sources

  • Orange Book
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL2103749 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Thrombin inhibitor Thrombin DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
ThrombosisD013927HP:0004419Recurrent thrombophlebitis4ATC
DailyMed
DailyMed
Angina, UnstableD000789EFO:1000985intermediate coronary syndrome4DailyMed
Aortic Valve StenosisD001024EFO:0000266aortic stenosis3ClinicalTrials
HemorrhageD006470MP:0001914hemorrhage3ClinicalTrials
Cardiovascular DiseasesD002318EFO:0000319cardiovascular disease3ClinicalTrials
ThrombocytopeniaD0139214DailyMed
DailyMed
Venous ThrombosisD020246HP:0004936Venous thrombosis2ClinicalTrials
Coronary Artery DiseaseD003324EFO:0000378coronary artery disease3ClinicalTrials
Hematologic DiseasesD006402HP:0001871abnormality of blood and blood-forming tissues3ClinicalTrials
Acute Coronary SyndromeD054058EFO:0005672acute coronary syndrome3ClinicalTrials
Myocardial InfarctionD009203EFO:0000612myocardial infarction3ClinicalTrials
Venous ThrombosisD020246EFO:0003907deep vein thrombosis2ClinicalTrials

Clinical Data

ClinicalTrials.gov BIVALIRUDIN
The Cochrane Collaboration BIVALIRUDIN

HELM Notation

CHEMBL2103749 HELM Notation
PEPTIDE1{[dF].P.R.P.G.G.G.G.N.G.D.F.E.E.I.P.E.E.Y.L}$$$$

The ChEMBL HELM monomer library is available to download here.

For more details about HELM Notation, please visit the HELM Homepage.

Compound Cross References

ATC B - BLOOD AND BLOOD FORMING ORGANS
B01 - ANTITHROMBOTIC AGENTS
B01A - ANTITHROMBOTIC AGENTS
B01AE - Direct thrombin inhibitors
B01AE06 - bivalirudin

ChemSpider ChemSpider:OIRCOABEOLEUMC-GEJPAHFPSA-N
DailyMed bivalirudin

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL2103749



ACToR 128270-60-0
Brenda 28560 151566 13504
ChEBI 59173
ChemicalBook CB9471951
DrugBank DB00006
DrugCentral 385
eMolecules 30513183
EPA CompTox Dashboard DTXSID00155847
Guide to Pharmacology 6470
IBM Patent System 2CB27038965CEA1120B075AFFF9A587A
MolPort MolPort-006-167-455
Nikkaji J1.204.802E
PharmGKB PA10032
PubChem 73952246 16129704 101041682
PubChem: Thomson Pharma 15363303 14891095
SureChEMBL SCHEMBL25739

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/OIRCOABEOLEUMC-GEJPAHFPSA-N spacer
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