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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201832
CHEMBL1201832
Compound Name ROMIPLOSTIM
ChEMBL Synonyms ROMIPLOSTIM | NPLATE
Max Phase 4 (Approved)
Trade Names NPLATE

Sources

  • British National Formulary
  • Manually Added Drugs
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL1201832 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Thrombopoietin receptor agonist Thrombopoietin receptor DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Lymphoma, Non-HodgkinD008228EFO:0005952non-Hodgkins lymphoma2ClinicalTrials
NeoplasmsD009369EFO:0000311cancer1ClinicalTrials
HemorrhageD006470MP:0001914hemorrhage4ATC
Anemia, AplasticD000741HP:0001915aplastic anemia2ClinicalTrials
Myelodysplastic SyndromesD009190EFO:0000198myelodysplastic syndrome2ClinicalTrials
LymphomaD008223EFO:0000574lymphoma1ClinicalTrials
Purpura, Thrombocytopenic, IdiopathicD016553EFO:0007160autoimmune thrombocytopenic purpura4ClinicalTrials
DailyMed

Clinical Data

ClinicalTrials.gov ROMIPLOSTIM
The Cochrane Collaboration ROMIPLOSTIM

Biological Sequence

Description Sequence
Romiplostim MDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYV DGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKA KGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLD SDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGGGGGIEGPTLR QWLAARAGGGGGGGGIEGPTLRQWLAARA

Compound Cross References

ATC B - BLOOD AND BLOOD FORMING ORGANS
B02 - ANTIHEMORRHAGICS
B02B - VITAMIN K AND OTHER HEMOSTATICS
B02BX - Other systemic hemostatics
B02BX04 - romiplostim

ChemSpider ChemSpider Identifier not yet assigned
DailyMed romiplostim
Wikipedia Romiplostim
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