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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201581
CHEMBL1201581
Compound Name INFLIXIMAB
ChEMBL Synonyms Remicade | INFLIXIMAB | cA2
Max Phase 4 (Approved)
Trade Names Remicade

Sources

  • British National Formulary
  • Clinical Candidates
  • Manually Added Drugs
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL1201581 compound icon
Drug Type:Antibody Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
TNF-alpha inhibitor TNF-alpha DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
COLITISD003092EFO:0003872COLITIS2ClinicalTrials
CROHN DISEASED003424EFO:0000384CROHN'S DISEASE4DailyMed
ClinicalTrials
SPONDYLARTHROPATHIESD025242EFO:0000706SPONDYLOARTHROPATHY2ClinicalTrials
SPONDYLITIS, ANKYLOSINGD013167EFO:0003898ANKYLOSING SPONDYLITIS4DailyMed
ClinicalTrials
UVEITISD014605EFO:1001231UVEITIS1ClinicalTrials
BEHCET SYNDROMED001528EFO:0003780BEHCET'S SYNDROME3ClinicalTrials
ENDOMETRIOSISD004715EFO:0001065ENDOMETRIOSIS2ClinicalTrials
BIPOLAR DISORDERD001714EFO:0000289BIPOLAR DISORDER2ClinicalTrials
DIABETIC RETINOPATHYD003930EFO:0003770DIABETIC RETINOPATHY3ClinicalTrials
GRAFT VS HOST DISEASED006086EFO:0004599ACUTE GRAFT VS. HOST DISEASE2ClinicalTrials
HIDRADENITIS SUPPURATIVAD017497EFO:1000710HIDRADENITIS SUPPURATIVA2ClinicalTrials
ARTHRITIS, RHEUMATOIDD001172EFO:0000685RHEUMATOID ARTHRITIS4DailyMed
ClinicalTrials
COLITIS, ULCERATIVED003093EFO:0000729ULCERATIVE COLITIS4ClinicalTrials
DailyMed
EOSINOPHILIC ESOPHAGITISD057765EFO:0004232EOSINOPHILIC ESOPHAGITIS2ClinicalTrials
PSORIASISD011565EFO:0000676PSORIASIS4ClinicalTrials
DailyMed
HEPATITIS CD006526EFO:0003047HEPATITIS C INFECTION2ClinicalTrials
ARTHRITIS, PSORIATICD015535EFO:0003778PSORIATIC ARTHRITIS4ClinicalTrials
DailyMed
BERYLLIOSISD001607EFO:0007168BERYLLIOSIS1ClinicalTrials
MUCOCUTANEOUS LYMPH NODE SYNDROMED009080EFO:0004246MUCOCUTANEOUS LYMPH NODE SYNDROME3ClinicalTrials

Clinical Data

ClinicalTrials.gov INFLIXIMAB
The Cochrane Collaboration INFLIXIMAB

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ATC L - ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L04 - IMMUNOSUPPRESSANTS
L04A - IMMUNOSUPPRESSANTS
L04AB - Tumor necrosis factor alpha (TNF-α) inhibitors
L04AB02 - infliximab

ChemSpider ChemSpider Identifier not yet assigned
DailyMed infliximab
Wikipedia Infliximab
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