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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201580
CHEMBL1201580
Compound Name ADALIMUMAB
ChEMBL Synonyms ADALIMUMAB | Humira | D2E7 | LU-200134
Max Phase 4 (Approved)
Trade Names Humira

Sources

  • British National Formulary
  • Clinical Candidates
  • Manually Added Drugs
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL1201580 compound icon
Drug Type:Antibody Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
TNF-alpha inhibitor TNF-alpha DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
ARTHRITIS, JUVENILED001171EFO:0002609CHRONIC CHILDHOOD ARTHRITIS3ClinicalTrials
COLITISD003092EFO:0003872COLITIS2ClinicalTrials
COLITIS, ULCERATIVED003093EFO:0000729ULCERATIVE COLITIS4ClinicalTrials
GLOMERULOSCLEROSIS, FOCAL SEGMENTALD005923EFO:0004236FOCAL SEGMENTAL GLOMERULOSCLEROSIS2ClinicalTrials
OSTEOARTHRITISD010003EFO:0002506OSTEOARTHRITIS3ClinicalTrials
ARTHRITIS, RHEUMATOIDD001172EFO:0000685RHEUMATOID ARTHRITIS4ClinicalTrials
CROHN DISEASED003424EFO:0000384CROHN'S DISEASE3ClinicalTrials
NETHERTON SYNDROMED056770Orphanet:634NETHERTON SYNDROME2ClinicalTrials
ARTHRITIS, PSORIATICD015535EFO:0003778PSORIATIC ARTHRITIS4ClinicalTrials
PYODERMAD011711HP:0000999PYODERMA2ClinicalTrials
SPONDYLITIS, ANKYLOSINGD013167EFO:0003898ANKYLOSING SPONDYLITIS4ClinicalTrials
CYSTITIS, INTERSTITIALD018856EFO:1000869CHRONIC INTERSTITIAL CYSTITIS3ClinicalTrials
UVEITISD014605EFO:1001231UVEITIS3ClinicalTrials
PAIND010146EFO:0003843PAIN3ClinicalTrials
PSORIASISD011565EFO:0000676PSORIASIS3ClinicalTrials
SARCOIDOSISD012507Orphanet:797SARCOIDOSIS2ClinicalTrials
HIDRADENITIS SUPPURATIVAD017497EFO:1000710HIDRADENITIS SUPPURATIVA3ClinicalTrials

Clinical Data

ClinicalTrials.gov ADALIMUMAB
The Cochrane Collaboration ADALIMUMAB

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ATC L - ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L04 - IMMUNOSUPPRESSANTS
L04A - IMMUNOSUPPRESSANTS
L04AB - Tumor necrosis factor alpha (TNF-α) inhibitors
L04AB04 - adalimumab

ChemSpider ChemSpider Identifier not yet assigned
DailyMed adalimumab
Wikipedia Adalimumab
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