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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201558
CHEMBL1201558
Compound Name INTERFERON ALFA-2B
ChEMBL Synonyms INTRON A | INTERFERON ALFA-2B | Viraferon | Intron-A | INTRON A HSA-FREE | SCH 30500
Max Phase 4 (Approved)
Trade Names Viraferon | INTRON A HSA-FREE | Intron-A | INTRON A

Sources

  • Manually Added Drugs
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names
  • WHO Anatomical Therapeutic Chemical Classification

Molecule Features

CHEMBL1201558 compound icon
Drug Type:Oligopeptide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Interferon alpha/beta receptor agonist Interferon alpha/beta receptor DailyMed PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Carcinoma, Renal CellD002292EFO:0002890renal carcinoma2ClinicalTrials
Hepatitis B, ChronicD019694EFO:0004197hepatitis B infection2ClinicalTrials
MelanomaD008545EFO:0000389cutaneous melanoma3ClinicalTrials
NeoplasmsD009369EFO:0000311cancer3ClinicalTrials
Carcinoma, Renal CellD002292EFO:0000681renal cell carcinoma2ClinicalTrials
InfectionD007239EFO:0000544infection2ClinicalTrials
LeukemiaD007938EFO:0000565leukemia1ClinicalTrials
Prostatic NeoplasmsD011471EFO:0001663prostate carcinoma2ClinicalTrials
Hepatitis C, ChronicD019698EFO:0004220Chronic Hepatitis C infection3ClinicalTrials
NeoplasmsD009369EFO:0000616neoplasm3ClinicalTrials
Breast NeoplasmsD001943EFO:0003869breast neoplasm1ClinicalTrials
Hepatitis B, ChronicD019694EFO:0004239chronic hepatitis B infection2ClinicalTrials
Hepatitis CD006526EFO:0003047hepatitis C infection2ClinicalTrials
Papillomavirus InfectionsD030361EFO:0001668human papilloma virus infection2ClinicalTrials
HIV InfectionsD015658EFO:0000764HIV infection3ClinicalTrials
LymphomaD008223EFO:0000574lymphoma1ClinicalTrials
Pancreatic NeoplasmsD010190EFO:0002618pancreatic carcinoma2ClinicalTrials
Carcinoma, HepatocellularD006528EFO:0000182hepatocellular carcinoma2ClinicalTrials
Leukemia, Biphenotypic, AcuteD015456EFO:0000209T-cell acute lymphoblastic leukemia2ClinicalTrials
MelanomaD008545EFO:0000756melanoma3ClinicalTrials
Ovarian NeoplasmsD010051EFO:0001075ovarian carcinoma1ClinicalTrials
Carcinoma, Renal CellD002292EFO:0000349clear cell renal carcinoma2ClinicalTrials
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveD015464EFO:0000339chronic myelogenous leukemia2ClinicalTrials
Multiple MyelomaD009101EFO:0001378multiple myeloma3ClinicalTrials

Clinical Data

ClinicalTrials.gov INTERFERON ALFA-2B
The Cochrane Collaboration INTERFERON ALFA-2B

Biological Sequence

Description Sequence
Interferon alpha-2 precursor MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFG FPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEA CVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNL QESLRSKE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Compound Cross References

ATC L - ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L03 - IMMUNOSTIMULANTS
L03A - IMMUNOSTIMULANTS
L03AB - Interferons
L03AB05 - interferon alfa-2b

ChemSpider ChemSpider Identifier not yet assigned
DailyMed interferon alfa-2b
Wikipedia Interferon_alfa-2b
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