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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1201470
CHEMBL1201470
Compound Name HYDROCODONE POLISTIREX
ChEMBL Synonyms HYDROCODONE POLISTIREX
Max Phase 4 (Approved)
Trade Names

Sources

  • Orange Book
  • USP Dictionary of USAN and International Drug Names

Molecule Features

CHEMBL1201470 compound icon
Drug Type:Polymer Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Opioid receptors; mu/kappa/delta agonist Opioid receptors; mu/kappa/delta FDA PubMed

Clinical Data

ClinicalTrials.gov HYDROCODONE POLISTIREX
The Cochrane Collaboration HYDROCODONE POLISTIREX

Target Predictions

The two tables below display ChEMBL single-protein targets which are predicted to interact with CHEMBL1201470. A 1uM and 10 uM cut-off have been applied to ChEMBL bioactivity data used to generate the respective models and the yellow coloured rows correspond to genuine predictions, i.e. targets not included in the original training set for this compound.


1uM


ChEMBL_ID Target Name Organism Score
CHEMBL233 Mu opioid receptor Homo sapiens 1.000
CHEMBL237 Kappa opioid receptor Homo sapiens 1.000
CHEMBL236 Delta opioid receptor Homo sapiens 1.000
CHEMBL3041 Mu opioid receptor Bos taurus 1.000
CHEMBL3952 Kappa opioid receptor Cavia porcellus 1.000
CHEMBL4354 Mu opioid receptor Cavia porcellus 1.000
CHEMBL3614 Kappa opioid receptor Rattus norvegicus 1.000
CHEMBL2858 Mu opioid receptor Mus musculus 1.000
CHEMBL269 Delta opioid receptor Rattus norvegicus 1.000
CHEMBL270 Mu opioid receptor Rattus norvegicus 1.000
CHEMBL4329 Kappa opioid receptor Mus musculus 1.000
CHEMBL3222 Delta opioid receptor Mus musculus 1.000
CHEMBL3998 Dopamine D2 receptor Bos taurus 0.235
CHEMBL1293237 Bloom syndrome protein Homo sapiens 0.211



10uM


ChEMBL_ID Target Name Organism Score
CHEMBL233 Mu opioid receptor Homo sapiens 1.000
CHEMBL236 Delta opioid receptor Homo sapiens 1.000
CHEMBL3041 Mu opioid receptor Bos taurus 1.000
CHEMBL3952 Kappa opioid receptor Cavia porcellus 1.000
CHEMBL4354 Mu opioid receptor Cavia porcellus 1.000
CHEMBL2858 Mu opioid receptor Mus musculus 1.000
CHEMBL237 Kappa opioid receptor Homo sapiens 1.000
CHEMBL3614 Kappa opioid receptor Rattus norvegicus 1.000
CHEMBL4329 Kappa opioid receptor Mus musculus 1.000
CHEMBL270 Mu opioid receptor Rattus norvegicus 1.000
CHEMBL269 Delta opioid receptor Rattus norvegicus 1.000
CHEMBL3222 Delta opioid receptor Mus musculus 1.000
CHEMBL1795167 Toll-like receptor 4 Mus musculus 0.994
CHEMBL3403 Butyrylcholinesterase Rattus norvegicus 0.980
CHEMBL4780 Acetylcholinesterase Torpedo californica 0.977
CHEMBL3459 Serotonin 1b (5-HT1b) receptor Rattus norvegicus 0.542
CHEMBL3998 Dopamine D2 receptor Bos taurus 0.394
CHEMBL1833 Serotonin 2b (5-HT2b) receptor Homo sapiens 0.255
CHEMBL3602 Sigma opioid receptor Rattus norvegicus 0.228
CHEMBL287 Sigma opioid receptor Homo sapiens 0.212

Compound Cross References

ChemSpider ChemSpider Identifier not yet assigned
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