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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1200952
CHEMBL1200952
Compound Name METHAMPHETAMINE HYDROCHLORIDE
ChEMBL Synonyms DESOXYEPHEDRINE HYDROCHLORIDE | METHYLAMFETAMINE HYDROCHLORIDE | DESOXYN | METHAMPHETAMINE HYDROCHLORIDE | METHAMPEX
Max Phase 4 (Approved)
Withdrawn Yes
Trade Names DESOXYN | METHAMPEX | METHAMPHETAMINE HYDROCHLORIDE
Molecular Formula C10H16ClN

Additional synonyms for CHEMBL1200952 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES Cl.CN[C@@H](C)Cc1ccccc1
Standard InChI InChI=1S/C10H15N.ClH/c1-9(11-2)8-10-6-4-3-5-7-10;/h3-7,9,11H ...
Download InChI
Standard InChI Key TWXDDNPPQUTEOV-FVGYRXGTSA-N

Sources

  • British National Formulary
  • Orange Book
  • PubChem BioAssays
  • USP Dictionary of USAN and International Drug Names
  • Withdrawn Drugs

Alternate Forms of Compound in ChEMBL


CHEMBL1200952

Molecule Features

CHEMBL1200952 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:Y Availability Type:Prescription-only

Withdrawal Information

Year
Country United States
Reason
Class

Mechanism of Action

Mechanism of Action ChEMBL Target References
Monoamine transporter inhibitor Monoamine transporter ISBN

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Amphetamine-Related DisordersD019969EFO:0004701metamphetamine dependence0ClinicalTrials
ClinicalTrials

Clinical Data

ClinicalTrials.gov METHAMPHETAMINE HYDROCHLORIDE
The Cochrane Collaboration METHAMPHETAMINE HYDROCHLORIDE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
149.2 149.1204 1.84 3 12.03 BASE


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
1 1 0 1 1 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 10.38 2.2 -.54 1 11 0.69

Structural Alerts

There are no structural alerts for CHEMBL1200952

Compound Cross References

ChemSpider ChemSpider:TWXDDNPPQUTEOV-FVGYRXGTSA-N
DailyMed methamphetamine hydrochloride
PubChem SID: 144206409

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1200952



ACToR 826-10-8
ChEBI 35340
eMolecules 592018
EPA CompTox Dashboard DTXSID8048864
FDA SRS 997F43Z9CV
PubChem 6857544 66124 57525347
PubChem: Thomson Pharma 26517037
SureChEMBL SCHEMBL42100

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/TWXDDNPPQUTEOV-FVGYRXGTSA-N spacer
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