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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1200826
CHEMBL1200826
Compound Name LITHIUM CARBONATE
ChEMBL Synonyms LITHIUM CARBONATE | PHASAL | LISKONUM | CP-15,467-61 | CAMCOLIT 400 | ESKALITH | CP-15467-61 | ESKALITH CR | LITHOTABS | LITHONATE | LITHOBID | LITHANE | CAMCOLIT 250
Max Phase 4 (Approved)
Trade Names CAMCOLIT 250 | ESKALITH | ESKALITH CR | LITHANE | LITHOBID | LITHONATE | LITHOTABS | LITHIUM CARBONATE | CAMCOLIT 400 | LISKONUM | PHASAL
Molecular Formula CLi2O3

Additional synonyms for CHEMBL1200826 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES [Li+].[Li+].[O-]C(=O)[O-]
Standard InChI InChI=1S/CH2O3.2Li/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
Standard InChI Key XGZVUEUWXADBQD-UHFFFAOYSA-L

Sources

  • British National Formulary
  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL1200826

Molecule Features

CHEMBL1200826 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:N First In Class:N Chirality:Unknown Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Glycogen synthase kinase-3 inhibitor Glycogen synthase kinase-3 FDA PubMed
Inositol-1(or 4)-monophosphatase 1 inhibitor Inositol-1(or 4)-monophosphatase 1 FDA PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
AggressionD000374EFO:0003015aggressive behavior3ClinicalTrials
AnxietyD001007EFO:0005230anxiety3ClinicalTrials
GliomaD005910EFO:0000326central nervous system cancer1ClinicalTrials
Brain NeoplasmsD001932EFO:0003833brain neoplasm2ClinicalTrials
Depressive DisorderD003866EFO:0003761unipolar depression3ClinicalTrials
Huntington DiseaseD006816Orphanet:399Huntington disease2ClinicalTrials
Psychotic DisordersD011618EFO:0005407psychosis4ATC
Conduct DisorderD019955EFO:0004216conduct disorder3ClinicalTrials
DementiaD003704HP:0000726dementia3ClinicalTrials
Spinocerebellar AtaxiasD020754Orphanet:98756Spinocerebellar ataxia type 22ClinicalTrials
Multiple System AtrophyD019578EFO:1001050multiple system atrophy2ClinicalTrials
Alzheimer DiseaseD000544EFO:0000249Alzheimers disease2ClinicalTrials
Amyotrophic Lateral SclerosisD000690EFO:0000253amyotrophic lateral sclerosis2ClinicalTrials
Bipolar DisorderD001714EFO:0000289bipolar disorder3ClinicalTrials
Multiple SclerosisD009103EFO:0003885multiple sclerosis1ClinicalTrials
Prostatic NeoplasmsD011471EFO:0001663prostate carcinoma1ClinicalTrials
SchizophreniaD012559EFO:0000692schizophrenia3ClinicalTrials
Small Cell Lung CarcinomaD055752EFO:0000702small cell lung carcinoma1ClinicalTrials
Thyroid NeoplasmsD013964EFO:0002892thyroid carcinoma2ClinicalTrials
Frontotemporal DementiaD057180Orphanet:282Frontotemporal dementia2ClinicalTrials
Niemann-Pick Disease, Type CD052556Orphanet:646Niemann-Pick disease type C1ClinicalTrials
Fractures, BoneD050723EFO:0003931bone fracture2ClinicalTrials
Machado-Joseph DiseaseD017827Orphanet:98757Spinocerebellar ataxia type 32ClinicalTrials
Spinocerebellar AtaxiasD020754Orphanet:98755Spinocerebellar ataxia type 12ClinicalTrials
Spinal Cord InjuriesD013119EFO:1001919Spinal cord injury2ClinicalTrials
StrokeD020521EFO:0000712stroke3ClinicalTrials
Supranuclear Palsy, ProgressiveD013494Orphanet:683Progressive supranuclear palsy1ClinicalTrials
Wounds and InjuriesD014947EFO:0000546injury1ClinicalTrials

Clinical Data

ClinicalTrials.gov LITHIUM CARBONATE
The Cochrane Collaboration LITHIUM CARBONATE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
73.9 74.0168 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL1200826

Compound Cross References

ATC N - NERVOUS SYSTEM
N05 - PSYCHOLEPTICS
N05A - ANTIPSYCHOTICS
N05AN - Lithium
N05AN01 - lithium

ChemSpider ChemSpider:XGZVUEUWXADBQD-UHFFFAOYSA-L
DailyMed lithium carbonate
PubChem SID: 8139879
Wikipedia Lithium_carbonate

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1200826



ACToR 12767-19-0 554-13-2
Brenda 172057
ChEBI 6504
ChemicalBook CB5852228
eMolecules 480443
EPA CompTox Dashboard DTXSID1023784
FDA SRS 2BMD2GNA4V
KEGG Ligand C07964
MolPort MolPort-003-927-648
Nikkaji J425A
PubChem 11125 516884
PubChem: Drugs of the Future 24714729
PubChem: Thomson Pharma 15146288
SureChEMBL SCHEMBL25389

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/XGZVUEUWXADBQD-UHFFFAOYSA-L spacer
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