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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1200644
CHEMBL1200644
Compound Name FONDAPARINUX SODIUM
ChEMBL Synonyms SR 90107A | FONDAPARINUX SODIUM | ARIXTRA | ORG 31540
Max Phase 4 (Approved)
Trade Names ARIXTRA | FONDAPARINUX SODIUM
Molecular Formula C31H43N3Na10O49S8

Additional synonyms for CHEMBL1200644 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]. ...
Download SMILES
Standard InChI InChI=1S/C31H53N3O49S8.10Na/c1-69-27-9(33-85(48,49)50)13(37) ...
Download InChI
Standard InChI Key XEKSTYNIJLDDAZ-JASSWCPGSA-D

Sources

  • British National Formulary
  • Orange Book
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL1200644

Molecule Features

CHEMBL1200644 compound icon
Drug Type:Oligosaccharide Rule of Five:N First In Class:N Chirality:Single Stereoisomer Prodrug:N Oral:N Parenteral:Y Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Antithrombin-III activator Antithrombin-III FDA

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Renal InsufficiencyD0514371ClinicalTrials
ClinicalTrials
Venous ThromboembolismD054556EFO:0004286venous thromboembolism3ClinicalTrials
ClinicalTrials
Venous ThrombosisD020246HP:0004936Venous thrombosis3ClinicalTrials
ClinicalTrials
Venous ThrombosisD020246EFO:0003907deep vein thrombosis3ClinicalTrials
Pulmonary EmbolismD011655EFO:0003827pulmonary embolism3ClinicalTrials

Clinical Data

ClinicalTrials.gov FONDAPARINUX SODIUM
The Cochrane Collaboration FONDAPARINUX SODIUM

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
1508.3 1506.9513 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL1200644

Compound Cross References

ChemSpider ChemSpider:XEKSTYNIJLDDAZ-JASSWCPGSA-D
DailyMed fondaparinux sodium

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1200644



Brenda 159945
ChemicalBook CB41456602
FDA SRS X0Q6N9USOZ
MolPort MolPort-006-167-583
Nikkaji J1.878.798I
PharmGKB PA164746297
PubChem 636380
PubChem: Drugs of the Future 12014866
PubChem: Thomson Pharma 16688608
SureChEMBL SCHEMBL4937

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/XEKSTYNIJLDDAZ-JASSWCPGSA-D spacer
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