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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1200406
CHEMBL1200406
Compound Name DIMENHYDRINATE
ChEMBL Synonyms DRAMAMINE | ANTEMIN | VERTIGO-VOMEX S | CHLORANAUTINE | DIMENHYDRINATE
Max Phase 4 (Approved)
Trade Names ANTEMIN | VERTIGO-VOMEX S | DRAMAMINE | DIMENHYDRINATE
Molecular Formula C24H28ClN5O3

Additional synonyms for CHEMBL1200406 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES CN(C)CCOC(c1ccccc1)c2ccccc2.CN3C(=O)N(C)c4nc(Cl)[nH]c4C3=O
Standard InChI InChI=1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6- ...
Download InChI
Standard InChI Key NFLLKCVHYJRNRH-UHFFFAOYSA-N

Sources

  • British National Formulary
  • DrugMatrix
  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL1200406

Molecule Features

CHEMBL1200406 compound icon
Drug Type:Natural Product-derived Rule of Five:N First In Class:N Chirality:Unknown Prodrug:N Oral:Y Parenteral:Y Topical:N Black Box:N Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Histamine H1 receptor antagonist Histamine H1 receptor PubMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Postoperative Nausea and VomitingD020250EFO:0004888post operative nausea and vomiting2ClinicalTrials

Clinical Data

ClinicalTrials.gov DIMENHYDRINATE
The Cochrane Collaboration DIMENHYDRINATE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
470 469.1881 - - - -


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
- - - - - -


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- - - - - - -0

Structural Alerts

There are no structural alerts for CHEMBL1200406

Compound Cross References

ChemSpider ChemSpider:NFLLKCVHYJRNRH-UHFFFAOYSA-N
DailyMed dimenhydrinate
PubChem SID: 11112942 SID: 144207521 SID: 17389041 SID: 26747407
Wikipedia Dimenhydrinate

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1200406



ACToR 133294-22-1
ChEBI 94848
eMolecules 901766
FDA SRS JB937PER5C
LINCS LSM-6066
MolPort MolPort-003-666-165
PubChem 10660
PubChem: Thomson Pharma 15356136
SureChEMBL SCHEMBL5128

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/NFLLKCVHYJRNRH-UHFFFAOYSA-N spacer
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