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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1200341
CHEMBL1200341
Compound Name INDECAINIDE HYDROCHLORIDE
ChEMBL Synonyms LY-135837 | INDECAINIDE HYDROCHLORIDE | RICAINIDE | DECABID
Max Phase 4 (Approved)
Trade Names DECABID
Molecular Formula C20H25ClN2O

Additional synonyms for CHEMBL1200341 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES Cl.CC(C)NCCCC1(C(=O)N)c2ccccc2c3ccccc13
Standard InChI InChI=1S/C20H24N2O.ClH/c1-14(2)22-13-7-12-20(19(21)23)17-10- ...
Download InChI
Standard InChI Key NXNSCUZKMVYAJQ-UHFFFAOYSA-N

Sources

  • Orange Book
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL1200341

Molecule Features

CHEMBL1200341 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Achiral Molecule Prodrug:N Oral:Y Parenteral:N Topical:N Black Box:N Availability Type:Discontinued

Mechanism of Action

Mechanism of Action ChEMBL Target References
Sodium channel alpha subunit blocker Sodium channel alpha subunit PubMed PubMed

Clinical Data

ClinicalTrials.gov INDECAINIDE HYDROCHLORIDE
The Cochrane Collaboration INDECAINIDE HYDROCHLORIDE

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
308.4 308.1889 3.22 6 55.12 BASE


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
2 2 0 3 3 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 10.61 3.87 1.02 2 23 0.81

Structural Alerts

There are 3 structural alerts for CHEMBL1200341. To view alerts please click here.

Compound Cross References

ChemSpider ChemSpider:NXNSCUZKMVYAJQ-UHFFFAOYSA-N

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1200341



ACToR 73681-12-6
EPA CompTox Dashboard DTXSID60223950
FDA SRS M76V0B96L5
PubChem 52194
SureChEMBL SCHEMBL121201

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/NXNSCUZKMVYAJQ-UHFFFAOYSA-N spacer
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