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ChEMBL Statistics
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Compound Report Card

Compound Name and Classification

Compound ID CHEMBL1083385
CHEMBL1083385
Compound Name CLOPIDOGREL BISULFATE
ChEMBL Synonyms CLOPIDOGREL BISULFATE | PLAVIX | SR 25990C
Max Phase 4 (Approved)
Trade Names CLOPIDOGREL BISULFATE | PLAVIX
Molecular Formula C16H18ClNO6S2

Additional synonyms for CHEMBL1083385 found using NCI Chemical Identifier Resolver

Compound Representations

Molfile Download MolFile
Canonical SMILES COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl.OS(=O)(=O)O
Standard InChI InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12) ...
Download InChI
Standard InChI Key FDEODCTUSIWGLK-RSAXXLAASA-N

Sources

  • Orange Book
  • PubChem BioAssays
  • Scientific Literature
  • USP Dictionary of USAN and International Drug Names

Alternate Forms of Compound in ChEMBL


CHEMBL1083385

Molecule Features

CHEMBL1083385 compound icon
Drug Type:Synthetic Small Molecule Rule of Five:Y First In Class:N Chirality:Single Stereoisomer Prodrug:Y Oral:Y Parenteral:N Topical:N Black Box:Y Availability Type:Prescription-only

Mechanism of Action

Mechanism of Action ChEMBL Target References
Purinergic receptor P2Y12 antagonist Purinergic receptor P2Y12 DailyMed

Indications

MESH Heading MESH ID EFO ID EFO Term Max phase for indication References
Angina, UnstableD000789EFO:1000985intermediate coronary syndrome4DailyMed
Acute Coronary SyndromeD054058EFO:0005672acute coronary syndrome4DailyMed
DailyMed
ClinicalTrials
Breast NeoplasmsD001943EFO:0003869breast neoplasm2ClinicalTrials
IschemiaD007511EFO:0000556ischemia4ClinicalTrials
DailyMed
Coronary Artery DiseaseD003324EFO:0000378coronary artery disease1ClinicalTrials
ClinicalTrials
Peripheral Arterial DiseaseD058729EFO:0004265peripheral arterial disease4ClinicalTrials
DailyMed
DailyMed
StrokeD020521EFO:0000712stroke4DailyMed
DailyMed
ClinicalTrials
Myocardial InfarctionD009203EFO:0000612myocardial infarction4ClinicalTrials
ClinicalTrials
DailyMed
DailyMed

Clinical Data

ClinicalTrials.gov CLOPIDOGREL BISULFATE
The Cochrane Collaboration CLOPIDOGREL BISULFATE

Compound Bioactivity Summary

Compound Assay Summary

Compound Target Summary

Calculated Compound Parent Properties

Mol. Weight Mol. Weight Monoisotopic ALogP #Rotatable Bonds Polar Surface Area Molecular Species
321.8 321.059 3.67 3 29.54 NEUTRAL


HBA HBD #Ro5 Violations HBA (Lipinski) HBD (Lipinski) #Ro5 Violations (Lipinski)
4 0 0 3 0 0


ACD Acidic pKa ACD Basic pKa ACD LogP ACD LogD pH7.4 Aromatic Rings Heavy Atoms QED Weighted
- 4.56 2.58 2.58 2 21 0.81

Structural Alerts

There are 1 structural alerts for CHEMBL1083385. To view alerts please click here.

Compound Cross References

ChemSpider ChemSpider:FDEODCTUSIWGLK-RSAXXLAASA-N
DailyMed clopidogrel bisulfate
PubChem SID: 144205123 SID: 170465231

UniChem Cross References

View the UniChem Connectivity matches for CHEMBL1083385



ACToR 120202-66-6 135046-48-9 144077-07-6
ChEBI 3759
ChemicalBook CB3341209 CB1341210 CB0341208
eMolecules 2723827
EPA CompTox Dashboard DTXSID4046024
FDA SRS 08I79HTP27
Mcule MCULE-2362021814
MolPort MolPort-000-784-171
PubChem 115366 24883467
PubChem: Drugs of the Future 12014240
PubChem: Thomson Pharma 14880252 14831602
Selleck Clopidogrel-bisulfate
SureChEMBL SCHEMBL33556

UniChem REST Service Call:
https://www.ebi.ac.uk/unichem/rest/verbose_inchikey/FDEODCTUSIWGLK-RSAXXLAASA-N spacer
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