{"accession": "P47870", "component_id": 47, "component_type": "PROTEIN", "description": "Gamma-aminobutyric acid receptor subunit beta-2", "go_slims": [{"go_id": "GO:0003674"}, {"go_id": "GO:0005575"}, {"go_id": "GO:0005886"}, {"go_id": "GO:0006810"}, {"go_id": "GO:0007267"}, {"go_id": "GO:0008150"}, {"go_id": "GO:0016020"}, {"go_id": "GO:0022607"}, {"go_id": "GO:0022857"}, {"go_id": "GO:0034330"}, {"go_id": "GO:0043226"}, {"go_id": "GO:0048856"}, {"go_id": "GO:0055085"}], "organism": "Homo sapiens", "protein_classifications": [{"protein_classification_id": 1173}], "sequence": "MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKIFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN", "target_component_synonyms": [{"component_synonym": "GABA(A) receptor subunit beta-2", "syn_type": "UNIPROT"}, {"component_synonym": "GABAAR subunit beta-2", "syn_type": "UNIPROT"}, {"component_synonym": "GABRB2", "syn_type": "GENE_SYMBOL"}, {"component_synonym": "Gamma-aminobutyric acid receptor subunit beta-2", "syn_type": "UNIPROT"}], "target_component_xrefs": [{"xref_id": "P47870", "xref_name": null, "xref_src_db": "AlphaFoldDB"}, {"xref_id": "P47870", "xref_name": null, "xref_src_db": "ExpressionAtlas"}, {"xref_id": "GO:0005886", "xref_name": "plasma membrane", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0016020", "xref_name": "membrane", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0030659", "xref_name": "cytoplasmic vesicle membrane", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0034707", "xref_name": "chloride channel complex", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0043005", "xref_name": "neuron projection", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0043197", "xref_name": "dendritic spine", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0045202", "xref_name": "synapse", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0045211", "xref_name": "postsynaptic membrane", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0070062", "xref_name": "extracellular exosome", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0098982", "xref_name": "GABA-ergic synapse", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0099634", "xref_name": "postsynaptic specialization membrane", "xref_src_db": "GoComponent"}, {"xref_id": "GO:1902495", "xref_name": "transmembrane transporter complex", "xref_src_db": "GoComponent"}, {"xref_id": "GO:1902711", "xref_name": "GABA-A receptor complex", "xref_src_db": "GoComponent"}, {"xref_id": "GO:0004890", "xref_name": "GABA-A receptor activity", "xref_src_db": "GoFunction"}, {"xref_id": "GO:0005230", "xref_name": "extracellular ligand-gated monoatomic ion channel activity", "xref_src_db": "GoFunction"}, {"xref_id": "GO:0005254", "xref_name": "chloride channel activity", "xref_src_db": "GoFunction"}, {"xref_id": "GO:0016917", "xref_name": "GABA receptor activity", "xref_src_db": "GoFunction"}, {"xref_id": "GO:0022851", "xref_name": "GABA-gated chloride ion channel activity", "xref_src_db": "GoFunction"}, {"xref_id": "GO:0030594", "xref_name": "neurotransmitter receptor activity", "xref_src_db": "GoFunction"}, {"xref_id": "GO:1904315", "xref_name": "transmitter-gated monoatomic ion channel 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"CHEMBL2111339"}, {"target_chembl_id": "CHEMBL2111370"}, {"target_chembl_id": "CHEMBL3885571"}, {"target_chembl_id": "CHEMBL3885572"}, {"target_chembl_id": "CHEMBL3885576"}, {"target_chembl_id": "CHEMBL4296044"}, {"target_chembl_id": "CHEMBL4296045"}, {"target_chembl_id": "CHEMBL4296046"}, {"target_chembl_id": "CHEMBL4523640"}, {"target_chembl_id": "CHEMBL4523641"}, {"target_chembl_id": "CHEMBL5303741"}], "tax_id": 9606}