Homo sapiensFibroblast growth factor 1CHEMBL2120P05230Fibroblast growth factor 1462PROTEINSINGLE PROTEINAcidic fibroblast growth factorUNIPROTaFGFUNIPROTECGFUNIPROTEndothelial cell growth factorUNIPROTFGF-1UNIPROTFGF1GENE_SYMBOLFGFAGENE_SYMBOL_OTHERFibroblast growth factor 1UNIPROTHBGF-1UNIPROTHeparin-binding growth factor 1UNIPROT3FGMAPDBe4QBCAPDBe3HOMAPDBe4Q9PAPDBe2HW9APDBe4QALAPDBe2AXMAPDBe4Q9GAPDBe3CQAAPDBe4XKIAPDBe3K1XAPDBe3OJMAPDBe1PZZAPDBe4QBVAPDBe1DJSAPDBe1P63APDBe2AQZAPDBe1AXMAPDBe1JQZAPDBe4QC4APDBe2HWAAPDBe1NZKAPDBe4QO3APDBe2HWMAPDBe3OJ2APDBe3CRGAPDBe3CRHAPDBe1Z4SAPDBe3CRIAPDBe1E0OAPDBe1RG8APDBe3BAOAPDBe2AFGAPDBe3BAQAPDBe3BB2APDBe2Q9XAPDBe3BADAPDBe1JT7APDBe1HKNAPDBe1JT5APDBe3BAGAPDBe1JT4APDBe3BAHAPDBe3JUTAPDBe1JT3APDBe4J23APDBe3OJVAPDBe1Q04APDBe1Q03APDBe1YTOAPDBe3BA4APDBe4YOLAPDBe2NTDAPDBe3BA5APDBe3BA7APDBe2HZ9APDBe3O3QAPDBe1EVTAPDBe1JY0APDBe3UDAAPDBe1RY7APDBe3FJHAPDBe3FJIAPDBe3FJJAPDBe1K5VAPDBe3FJKAPDBe1K5UAPDBe3UD7APDBe4Q91APDBe3UD8APDBe3UD9APDBe3FJAAPDBe3B9UAPDBe3FJBAPDBe3CU1APDBe3FJCAPDBe3FJDAPDBe1M16APDBe3FJEAPDBe3FJFAPDBe3FJ8APDBe1Z2VAPDBe3FJ9APDBe3BAUAPDBe3BAVAPDBe1JTCAPDBeGO:0008284positive regulation of cell population proliferationGoProcessGO:0008543fibroblast growth factor receptor signaling pathwayGoProcessGO:0005104fibroblast growth factor receptor bindingGoFunctionGO:0005178integrin bindingGoFunctionGO:0005515protein bindingGoFunctionGO:0008083growth factor activityGoFunctionGO:0008201heparin bindingGoFunctionGO:0030544Hsp70 protein bindingGoFunctionGO:0044548S100 protein bindingGoFunctionGO:0001525angiogenesisGoProcessGO:0001759organ inductionGoProcessGO:0007165signal transductionGoProcessGO:0009653anatomical structure morphogenesisGoProcessGO:0010595positive regulation of endothelial cell migrationGoProcessGO:0022008neurogenesisGoProcessGO:0030154cell differentiationGoProcessGO:0030324lung developmentGoProcessGO:0030334regulation of cell migrationGoProcessGO:0030335positive regulation of cell migrationGoProcessGO:0032148activation of protein kinase B activityGoProcessGO:0034605cellular response to heatGoProcessGO:0043406positive regulation of MAP kinase activityGoProcessGO:0043410positive regulation of MAPK cascadeGoProcessGO:0045542positive regulation of cholesterol biosynthetic processGoProcessGO:0045766positive regulation of angiogenesisGoProcessGO:0045944positive regulation of transcription by RNA polymerase IIGoProcessGO:0050673epithelial cell proliferationGoProcessGO:0050679positive regulation of epithelial cell proliferationGoProcessGO:0051781positive regulation of cell divisionGoProcessGO:0060681branch elongation involved in ureteric bud branchingGoProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeGoProcessGO:0072163mesonephric epithelium developmentGoProcessGO:1901509regulation of endothelial tube morphogenesisGoProcessGO:1902533positive regulation of intracellular signal transductionGoProcessGO:1903672positive regulation of sprouting angiogenesisGoProcessGO:2000347positive regulation of hepatocyte proliferationGoProcessGO:2000544regulation of endothelial cell chemotaxis to fibroblast growth factorGoProcessGO:0005615extracellular spaceGoComponentGO:0005634nucleusGoComponentGO:0005737cytoplasmGoComponentGO:0005576extracellular regionGoComponentGO:0005654nucleoplasmGoComponentGO:0005829cytosolGoComponentGO:0005938cell cortexGoComponentPA28105fibroblast growth factor 1PharmGKBB2R5T0Fibroblast growth factor 1UniProtD3DQF2Fibroblast growth factor 1UniProtP07502Fibroblast growth factor 1UniProtQ16588Fibroblast growth factor 1UniProtP05230Fibroblast growth factor 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:3665FGF1HGNCR-HSA-109704PI3K CascadeReactomeR-HSA-1257604PIP3 activates AKT signalingReactomeR-HSA-1839122Signaling by activated point mutants of FGFR1ReactomeR-HSA-1839130Signaling by activated point mutants of FGFR3ReactomeR-HSA-190322FGFR4 ligand binding and activationReactomeR-HSA-190370FGFR1b ligand binding and activationReactomeR-HSA-190371FGFR3b ligand binding and activationReactomeR-HSA-190372FGFR3c ligand binding and activationReactomeR-HSA-190373FGFR1c ligand binding and activationReactomeR-HSA-190375FGFR2c ligand binding and activationReactomeR-HSA-190377FGFR2b ligand binding and activationReactomeR-HSA-2033519Activated point mutants of FGFR2ReactomeR-HSA-2219530Constitutive Signaling by Aberrant PI3K in CancerReactomeR-HSA-5654219Phospholipase C-mediated cascade: FGFR1ReactomeR-HSA-5654221Phospholipase C-mediated cascade, FGFR2ReactomeR-HSA-5654227Phospholipase C-mediated cascade, FGFR3ReactomeR-HSA-5654228Phospholipase C-mediated cascade, FGFR4ReactomeR-HSA-5654687Downstream signaling of activated FGFR1ReactomeR-HSA-5654688SHC-mediated cascade:FGFR1ReactomeR-HSA-5654689PI-3K cascade:FGFR1ReactomeR-HSA-5654693FRS-mediated FGFR1 signalingReactomeR-HSA-5654695PI-3K cascade:FGFR2ReactomeR-HSA-5654699SHC-mediated cascade:FGFR2ReactomeR-HSA-5654700FRS-mediated FGFR2 signalingReactomeR-HSA-5654704SHC-mediated cascade:FGFR3ReactomeR-HSA-5654706FRS-mediated FGFR3 signalingReactomeR-HSA-5654710PI-3K cascade:FGFR3ReactomeR-HSA-5654712FRS-mediated FGFR4 signalingReactomeR-HSA-5654719SHC-mediated cascade:FGFR4ReactomeR-HSA-5654720PI-3K cascade:FGFR4ReactomeR-HSA-5654726Negative regulation of FGFR1 signalingReactomeR-HSA-5654727Negative regulation of FGFR2 signalingReactomeR-HSA-5654732Negative regulation of FGFR3 signalingReactomeR-HSA-5654733Negative regulation of FGFR4 signalingReactomeR-HSA-5655253Signaling by FGFR2 in diseaseReactomeR-HSA-5655302Signaling by FGFR1 in diseaseReactomeR-HSA-5655332Signaling by FGFR3 in diseaseReactomeR-HSA-5673001RAF/MAP kinase cascadeReactomeR-HSA-6811558PI5P, PP2A and IER3 Regulate PI3K/AKT SignalingReactomeR-HSA-8851708Signaling by FGFR2 IIIa TMReactomeP05230PharosP05230ExpressionAtlasIPR002209Fibroblast_GF_famInterProIPR008996IL1/FGFInterProPTHR11486FIBROBLAST GROWTH FACTORPANTHERPF00167FGFPfamSINGLE PROTEIN9606