{"atc_classifications": ["H01CA01", "V04CM01"], "availability_type": 0, "biotherapeutic": {"biocomponents": [{"component_id": 29279, "component_type": "Protein", "description": "Sequence", "organism": null, "sequence": "QHWSYGLRPG", "tax_id": null}], "description": "Progonadoliberin I precursor", "helm_notation": "PEPTIDE1{[Glp].H.W.S.Y.G.L.R.P.G.[am]}$$$$", "molecule_chembl_id": "CHEMBL1007"}, "black_box_warning": 0, "chemical_probe": 0, "chirality": 1, "cross_references": [], "dosed_ingredient": false, "first_approval": 1982, "first_in_class": 0, "helm_notation": "PEPTIDE1{[Glp].H.W.S.Y.G.L.R.P.G.[am]}$$$$", "inorganic_flag": 0, "max_phase": "4.0", "molecule_chembl_id": "CHEMBL1007", "molecule_hierarchy": {"active_chembl_id": "CHEMBL1007", "molecule_chembl_id": "CHEMBL1007", "parent_chembl_id": "CHEMBL1007"}, "molecule_properties": {"alogp": null, "aromatic_rings": null, "full_molformula": "C55H75N17O13", "full_mwt": "1182.31", "hba": null, "hbd": null, "heavy_atoms": null, 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0 0 0 0 0 0 0 0 0\n 12.9250 -3.1542 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 7.4833 -0.6750 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 3.8042 -4.2083 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0\n 12.7042 -3.8250 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 10.5458 -3.8625 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 1.8458 -0.4417 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 9.3250 -1.7375 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 3.2667 -0.4667 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 11.1625 -4.9250 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 11.1625 -4.2167 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 9.3250 -1.0292 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 9.9375 -2.0917 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 2.2125 0.1625 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 2.9250 0.1542 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0\n 2 1 1 0\n 3 31 1 0\n 4 16 1 0\n 5 11 1 0\n 6 14 1 0\n 7 17 1 0\n 8 15 1 0\n 9 27 1 0\n 10 1 1 0\n 12 11 1 6\n 12 4 1 0\n 13 18 1 0\n 20 14 1 1\n 19 15 1 6\n 25 16 1 1\n 23 17 1 6\n 18 3 2 0\n 19 6 1 0\n 20 5 1 0\n 10 21 1 6\n 22 38 1 0\n 23 2 1 0\n 24 43 1 0\n 25 22 1 0\n 26 7 1 0\n 27 8 1 1\n 28 58 1 0\n 29 9 1 0\n 30 3 1 0\n 20 31 1 0\n 26 32 1 1\n 33 34 1 0\n 19 34 1 0\n 35 33 1 0\n 36 32 1 0\n 37 21 1 0\n 38 59 1 0\n 39 35 1 0\n 40 30 2 0\n 41 60 1 0\n 42 28 2 0\n 43 33 2 0\n 44 2 2 0\n 45 4 2 0\n 46 7 2 0\n 47 6 2 0\n 48 5 2 0\n 49 8 2 0\n 25 50 1 0\n 51 21 2 0\n 52 22 2 0\n 26 53 1 0\n 54 29 2 0\n 55 36 2 0\n 56 41 2 0\n 57 27 1 0\n 58 80 1 0\n 59 36 1 0\n 60 37 1 0\n 61 28 1 0\n 62 1 1 0\n 63 57 1 0\n 64 41 1 0\n 65 50 1 0\n 66 70 2 0\n 12 67 1 0\n 68 65 1 0\n 69 65 2 0\n 70 69 1 0\n 71 68 2 0\n 72 10 1 0\n 73 66 1 0\n 74 67 1 0\n 75 62 1 0\n 23 76 1 0\n 77 30 1 0\n 78 53 1 0\n 79 40 1 0\n 80 81 1 0\n 81 76 1 0\n 82 78 1 0\n 83 78 1 0\n 84 77 2 0\n 85 84 1 0\n 72 75 1 0\n 66 71 1 0\n 13 40 1 0\n 79 85 2 0\n 39 24 2 0\n 29 63 1 0\nM END\n> \nCHEMBL1007\n\n> \nGONADORELIN", "standard_inchi": "InChI=1S/C55H75N17O13/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1", "standard_inchi_key": "XLXSAKCOAKORKW-AQJXLSMYSA-N"}, "molecule_synonyms": [{"molecule_synonym": "Fertiral lh-rh", "syn_type": "TRADE_NAME", "synonyms": "FERTIRAL LH-RH"}, {"molecule_synonym": "Gonadorelin", "syn_type": "ATC", "synonyms": "GONADORELIN"}, {"molecule_synonym": "Gonadorelin", "syn_type": "BAN", "synonyms": "GONADORELIN"}, {"molecule_synonym": "Gonadorelin", "syn_type": "BNF", "synonyms": "GONADORELIN"}, {"molecule_synonym": "Gonadorelin", "syn_type": "INN", "synonyms": "GONADORELIN"}, {"molecule_synonym": "Gonadorelin", "syn_type": "MERCK_INDEX", "synonyms": "GONADORELIN"}, {"molecule_synonym": "Gonadorelin", "syn_type": "OTHER", "synonyms": "GONADORELIN"}, {"molecule_synonym": "Gonadorelina", "syn_type": "INN_SPANISH", "synonyms": "GONADORELINA"}, {"molecule_synonym": "Gonadorelin decapeptide", "syn_type": "OTHER", "synonyms": "GONADORELIN DECAPEPTIDE"}, {"molecule_synonym": "Gonadoreline", "syn_type": "INN_FRENCH", "synonyms": "GONADORELINE"}, {"molecule_synonym": "Gonadotropin-releasing hormone", "syn_type": "OTHER", "synonyms": "GONADOTROPIN-RELEASING HORMONE"}, {"molecule_synonym": "Relefact lh-rh", "syn_type": "TRADE_NAME", "synonyms": "RELEFACT LH-RH"}], "molecule_type": "Protein", "natural_product": 1, "oral": false, "orphan": 0, "parenteral": true, "polymer_flag": 0, "pref_name": "GONADORELIN", "prodrug": 0, "structure_type": "BOTH", "therapeutic_flag": true, "topical": false, "usan_stem": "-relin", "usan_stem_definition": "prehormones or hormone-release stimulating peptides", "usan_substem": "-relin", "usan_year": 1975, "veterinary": 0, "withdrawn_flag": false}