12592949CHEMBL3071788Inhibition of AChE (unknown origin)BBAO_0000190BAO_0000357single protein formatC[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(-c4ccc(O)c(O)c4)oc4cc(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1OCHEMBL3045386Med Chem Res201312.970.259.612.94CHEMBL226335RUTINCHEMBL2263357.92http://www.openphacts.org/units/Nanomolar1837678=11=IC50nM12.0CHEMBL220Homo sapiensAcetylcholinesterase9606IC50uMUO_00000650.012INHIBITORNegatively effects (inhibits) the normal functioning of the protein e.g., prevention of enzymatic reaction or activation of downstream pathwayNEGATIVE MODULATOR25030897CHEMBL5241710Inhibition of BACE1 (unknown origin)BBAO_0000190BAO_0000357single protein formatC[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(-c4ccc(O)c(O)c4)oc4cc(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1OCHEMBL5241074Eur J Med Chem202113.790.2710.113.13CHEMBL226335RUTINCHEMBL2263358.42http://www.openphacts.org/units/Nanomolar3919145=11=IC50nM3.8CHEMBL4822Homo sapiensBeta-secretase 19606IC50uMUO_00000650.0038INHIBITORNegatively effects (inhibits) the normal functioning of the protein e.g., prevention of enzymatic reaction or activation of downstream pathwayNEGATIVE MODULATOR29087337CHEMBL6081502Binding affinity to HMGB1 (unknown origin) assessed as dissociation constant by SPR analysisBBAO_0000034BAO_0000357single protein formatC[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(-c4ccc(O)c(O)c4)oc4cc(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1OCHEMBL6078690J Med Chem202410.790.218.282.44CHEMBL226335RUTINCHEMBL2263356.58http://www.openphacts.org/units/Nanomolar4665363=11=KdnM260.0CHEMBL2311236Homo sapiensHigh mobility group protein B19606KduMUO_00000650.26203