620530CHEMBL849277Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine induced climbingFBAO_0000193BAO_0000019assay formatCN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1CHEMBL1127609J Med Chem1994CHEMBL42CLOZAPINECHEMBL42155116=1=Ratio3.5CHEMBL612545UncheckedRatio3.5595387CHEMBL849277Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine induced climbingFBAO_0000193BAO_0000019assay formatO=c1c2ccccc2cnn1CCCCN1CCN(c2nsc3ccccc23)CC1CHEMBL1127609J Med Chem1994CHEMBL85647CHEMBL85647155112=1=Ratio2.5CHEMBL612545UncheckedRatio2.51246428CHEMBL652263Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2ccccc2C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL276002CHEMBL2760028.30http://www.openphacts.org/units/Nanomolar6565=11=KdnM5.012CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000658.31210636CHEMBL881732Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine-induced climbing.FBAO_0000193BAO_0000019assay formatNc1cccnc1C(=O)NCCCCN1CCN(c2nsc3ccccc23)CC1CHEMBL1129407J Med Chem1996CHEMBL142211CHEMBL142211276895=1=Ratio5.0CHEMBL612545UncheckedRatio5.0624303CHEMBL849277Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine induced climbingFBAO_0000193BAO_0000019assay formatO=c1c2ccccc2nnn1CCCCN1CCN(c2nsc3ccccc23)CC1CHEMBL1127609J Med Chem1994CHEMBL314043CHEMBL314043155109=1=Ratio3.0CHEMBL612545UncheckedRatio3.01188294CHEMBL849278Ratio of ED50 for antagonism of apomorphine-induced stereotypy to ED50 for antagonism of apomorphine-induced climbing.FBAO_0000193BAO_0000019assay formatCc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2CHEMBL1129407J Med Chem1996CHEMBL85RISPERIDONECHEMBL85276903=1=Ratio4.0CHEMBL612545UncheckedRatio4.01257790CHEMBL652263Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(CCCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL9642SC-52892CHEMBL96428.68http://www.openphacts.org/units/Nanomolar6554=11=KdnM2.089CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000658.681227205CHEMBL652263Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(CCCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL9714SC-51895CHEMBL97148.65http://www.openphacts.org/units/Nanomolar6553=11=KdnM2.239CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000658.651249206CHEMBL652263Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL9771CHEMBL97718.10http://www.openphacts.org/units/Nanomolar6555=11=KdnM7.943CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000658.1599271CHEMBL849277Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine induced climbingFBAO_0000193BAO_0000019assay formatO=C1Cc2ccccc2C(=O)N1CCCCN1CCN(c2nsc3ccccc23)CC1CHEMBL1127609J Med Chem1994CHEMBL83454CHEMBL83454155102=1=Ratio3.3CHEMBL612545UncheckedRatio3.3610280CHEMBL849277Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine induced climbingFBAO_0000193BAO_0000019assay formatO=C1c2ccccc2CN1CCCCN1CCN(c2nsc3ccccc23)CC1CHEMBL1127609J Med Chem1994CHEMBL41626CHEMBL41626155105=1=Ratio3.9CHEMBL612545UncheckedRatio3.91201326CHEMBL881732Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine-induced climbing.FBAO_0000193BAO_0000019assay formatNc1ccsc1C(=O)NCCCCN1CCN(c2nsc3ccccc23)CC1CHEMBL1129407J Med Chem1996CHEMBL141438CHEMBL141438276891=1=Ratio6.0CHEMBL612545UncheckedRatio6.01257856CHEMBL652264Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows Non-competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2ccccc2C(C)(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL427808CHEMBL4278089.00http://www.openphacts.org/units/Nanomolar6563=11=KdnM1.0CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000659.0629438CHEMBL849277Ratio of ED50 for antagonism of apomorphine induced stereotypy to ED50 for antagonism of apomorphine induced climbingFBAO_0000193BAO_0000019assay formatO=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1CHEMBL1127609J Med Chem1994CHEMBL54HALOPERIDOLCHEMBL54155115=1=Ratio1.8CHEMBL612545UncheckedRatio1.81187068CHEMBL849278Ratio of ED50 for antagonism of apomorphine-induced stereotypy to ED50 for antagonism of apomorphine-induced climbing.FBAO_0000193BAO_0000019assay formatCN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1CHEMBL1129407J Med Chem1996CHEMBL42CLOZAPINECHEMBL42276894=1=Ratio4.0CHEMBL612545UncheckedRatio4.01256640CHEMBL652263Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2c(C(C)C)cccc2C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL274082CHEMBL2740827.10http://www.openphacts.org/units/Nanomolar6560=11=KdnM79.43CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000657.11261483CHEMBL652263Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2ccccc2C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL276689CHEMBL2766898.70http://www.openphacts.org/units/Nanomolar6564=11=KdnM1.995CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000658.71236088CHEMBL652264Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows Non-competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2c(C)cccc2C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL430152CHEMBL4301529.20http://www.openphacts.org/units/Nanomolar6562=11=KdnM0.631CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000659.21253805CHEMBL652264Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows Non-competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2ccccc2CC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL267809CHEMBL2678098.70http://www.openphacts.org/units/Nanomolar6566=11=KdnM1.995CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000658.71228527CHEMBL652264Compound was tested for antagonism of Angiotensin II-contracted rabbit aortic rings. Compound shows Non-competitive receptor Antagonism.FBAO_0000034BAO_0000019assay formatCCCCc1cn(-c2c(CC)cccc2CC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1CHEMBL1126489Bioorg Med Chem Lett1993CHEMBL274668CHEMBL2746688.70http://www.openphacts.org/units/Nanomolar6561=11=KdnM1.995CHEMBL2094256Homo sapiensAngiotensin II receptor9606pA2UO_00000658.720/chembl/api/data/activity/search?limit=20&offset=20&q=antagonism10000